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Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3+CD8+ Tregs.
Sci Immunol. 2021 Jun 4;6(60):eabd3774. doi: 10.1126/sciimmunol.abd3774.
Sci Immunol. 2021.
PMID: 34088744
Vectorized Treg-depleting αCTLA-4 elicits antigen cross-presentation and CD8+ T cell immunity to reject 'cold' tumors.
Semmrich M, Marchand JB, Fend L, Rehn M, Remy C, Holmkvist P, Silvestre N, Svensson C, Kleinpeter P, Deforges J, Junghus F, Cleary KL, Bodén M, Mårtensson L, Foloppe J, Teige I, Quéméneur E, Frendéus B.
Semmrich M, et al. Among authors: holmkvist p.
J Immunother Cancer. 2022 Jan;10(1):e003488. doi: 10.1136/jitc-2021-003488.
J Immunother Cancer. 2022.
PMID: 35058324
Free PMC article.
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IL-18Rα-deficient CD4(+) T cells induce intestinal inflammation in the CD45RB(hi) transfer model of colitis despite impaired innate responsiveness.
Holmkvist P, Pool L, Hägerbrand K, Agace WW, Rivollier A.
Holmkvist P, et al.
Eur J Immunol. 2016 Jun;46(6):1371-82. doi: 10.1002/eji.201545957. Epub 2016 May 6.
Eur J Immunol. 2016.
PMID: 27062602
Free article.
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A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality.
Holmkvist P, Roepstorff K, Uronen-Hansson H, Sandén C, Gudjonsson S, Patschan O, Grip O, Marsal J, Schmidtchen A, Hornum L, Erjefält JS, Håkansson K, Agace WW.
Holmkvist P, et al.
Mucosal Immunol. 2015 May;8(3):545-58. doi: 10.1038/mi.2014.87. Epub 2014 Oct 1.
Mucosal Immunol. 2015.
PMID: 25269704
Free PMC article.
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