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CD8 co-receptor promotes susceptibility of CD8+ T cells to transforming growth factor-β (TGF-β)-mediated suppression.
Cancer Immunol Immunother. 2011 Feb;60(2):291-7. doi: 10.1007/s00262-010-0962-6. Epub 2010 Dec 31.
Cancer Immunol Immunother. 2011.
PMID: 21193909
Free PMC article.
CD8(+) T cells sabotage their own memory potential through IFN-γ-dependent modification of the IL-12/IL-15 receptor α axis on dendritic cells.
Kohlhapp FJ, Zloza A, O'Sullivan JA, Moore TV, Lacek AT, Jagoda MC, McCracken J, Cole DJ, Guevara-Patiño JA.
Kohlhapp FJ, et al. Among authors: jagoda mc.
J Immunol. 2012 Apr 15;188(8):3639-47. doi: 10.4049/jimmunol.1101580. Epub 2012 Mar 19.
J Immunol. 2012.
PMID: 22430740
Free PMC article.
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Immunoglobulin-like transcript 2 (ILT2) is a biomarker of therapeutic response to oncolytic immunotherapy with vaccinia viruses.
Zloza A, Kim DW, Kim-Schulze S, Jagoda MC, Monsurro V, Marincola FM, Kaufman HL.
Zloza A, et al. Among authors: jagoda mc.
J Immunother Cancer. 2014 Jan 27;2:1. doi: 10.1186/2051-1426-2-1. eCollection 2014.
J Immunother Cancer. 2014.
PMID: 24829758
Free PMC article.
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NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses.
Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Polić B, Al-Harthi L, Sperling AI, Guevara-Patiño JA.
Zloza A, et al. Among authors: jagoda mc.
Nat Med. 2012 Feb 26;18(3):422-8. doi: 10.1038/nm.2683.
Nat Med. 2012.
PMID: 22366950
Free PMC article.
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Engagement of NK receptor NKG2D, but not 2B4, results in self-reactive CD8+ T cells and autoimmune vitiligo.
Zloza A, Lyons GE, Chlewicki LK, Kohlhapp FJ, O'Sullivan JA, Lacek AT, Moore TV, Jagoda MC, Kumar V, Guevara-Patiño JA.
Zloza A, et al. Among authors: jagoda mc.
Autoimmunity. 2011 Dec;44(8):599-606. doi: 10.3109/08916934.2011.593599. Epub 2011 Sep 13.
Autoimmunity. 2011.
PMID: 21913803
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Results of a randomized phase I gene therapy clinical trial of nononcolytic fowlpox viruses encoding T cell costimulatory molecules.
Kaufman HL, Kim DW, Kim-Schulze S, DeRaffele G, Jagoda MC, Broucek JR, Zloza A.
Kaufman HL, et al. Among authors: jagoda mc.
Hum Gene Ther. 2014 May;25(5):452-60. doi: 10.1089/hum.2013.217. Epub 2014 Mar 26.
Hum Gene Ther. 2014.
PMID: 24484178
Free PMC article.
Clinical Trial.
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Development of tumor-infiltrating CD8+ T cell memory precursor effector cells and antimelanoma memory responses are the result of vaccination and TGF-β blockade during the perioperative period of tumor resection.
Bellavance EC, Kohlhapp FJ, Zloza A, O'Sullivan JA, McCracken J, Jagoda MC, Lacek AT, Posner MC, Guevara-Patino JA.
Bellavance EC, et al. Among authors: jagoda mc.
J Immunol. 2011 Mar 15;186(6):3309-16. doi: 10.4049/jimmunol.1002549. Epub 2011 Feb 2.
J Immunol. 2011.
PMID: 21289306
Free PMC article.
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