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Page 1
Case Report: Targeting of individual somatic tumor mutations by multipeptide vaccination tailored for HLA class I and II presentation induces strong CD4 and CD8 T-cell responses in a patient with metastatic castration sensitive prostate cancer.
Zelba H, Rabsteyn A, Bartsch O, Kyzirakos C, Kayser S, Seibold M, Harter J, Latzer P, Hadaschik D, Battke F, Golf A, Rettig MB, Biskup S. Zelba H, et al. Among authors: kyzirakos c. Front Immunol. 2023 Oct 18;14:1271449. doi: 10.3389/fimmu.2023.1271449. eCollection 2023. Front Immunol. 2023. PMID: 37920460 Free PMC article.
Use of plasma ctDNA as a potential biomarker for longitudinal monitoring of a patient with metastatic high-risk upper tract urothelial carcinoma receiving pembrolizumab and personalized neoepitope-derived multipeptide vaccinations: a case report.
Blumendeller C, Boehme J, Frick M, Schulze M, Rinckleb A, Kyzirakos C, Kayser S, Kopp M, Kelkenberg S, Pieper N, Bartsch O, Hadaschick D, Battke F, Stenzl A, Biskup S. Blumendeller C, et al. Among authors: kyzirakos c. J Immunother Cancer. 2021 Jan;9(1):e001406. doi: 10.1136/jitc-2020-001406. J Immunother Cancer. 2021. PMID: 33431630 Free PMC article.
Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab.
Schlegel P, Lang P, Zugmaier G, Ebinger M, Kreyenberg H, Witte KE, Feucht J, Pfeiffer M, Teltschik HM, Kyzirakos C, Feuchtinger T, Handgretinger R. Schlegel P, et al. Among authors: kyzirakos c. Haematologica. 2014 Jul;99(7):1212-9. doi: 10.3324/haematol.2013.100073. Epub 2014 Apr 11. Haematologica. 2014. PMID: 24727818 Free PMC article.
Favorable NK cell activity after haploidentical hematopoietic stem cell transplantation in stage IV relapsed Ewing's sarcoma patients.
Schlegel P, Feuchtinger T, Nitschke-Gérard C, Seidel UJ, Lang AM, Kyzirakos C, Teltschik HM, Ebinger M, Schumm M, Koscielniak E, Handgretinger R, Lang P. Schlegel P, et al. Among authors: kyzirakos c. Bone Marrow Transplant. 2015 Jun;50 Suppl 2:S72-6. doi: 10.1038/bmt.2015.100. Bone Marrow Transplant. 2015. PMID: 26039213 Clinical Trial.
Circulating CD4+ T cells that produce IL4 or IL17 when stimulated by melan-A but not by NY-ESO-1 have negative impacts on survival of patients with stage IV melanoma.
Zelba H, Weide B, Martens A, Derhovanessian E, Bailur JK, Kyzirakos C, Pflugfelder A, Eigentler TK, Di Giacomo AM, Maio M, Aarntzen EH, de Vries J, Sucker A, Schadendorf D, Büttner P, Garbe C, Pawelec G. Zelba H, et al. Among authors: kyzirakos c. Clin Cancer Res. 2014 Aug 15;20(16):4390-9. doi: 10.1158/1078-0432.CCR-14-1015. Epub 2014 Jun 17. Clin Cancer Res. 2014. PMID: 24938524
Adoptive transfer of epstein-barr virus (EBV) nuclear antigen 1-specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation.
Icheva V, Kayser S, Wolff D, Tuve S, Kyzirakos C, Bethge W, Greil J, Albert MH, Schwinger W, Nathrath M, Schumm M, Stevanovic S, Handgretinger R, Lang P, Feuchtinger T. Icheva V, et al. Among authors: kyzirakos c. J Clin Oncol. 2013 Jan 1;31(1):39-48. doi: 10.1200/JCO.2011.39.8495. Epub 2012 Nov 19. J Clin Oncol. 2013. PMID: 23169501