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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1911 1
1944 1
1947 1
1948 2
1950 1
1951 2
1952 1
1953 1
1954 4
1955 5
1957 1
1958 1
1959 3
1960 3
1961 3
1962 6
1963 1
1964 5
1965 10
1966 5
1967 4
1968 11
1969 8
1970 3
1971 8
1972 6
1973 12
1974 5
1975 6
1976 5
1977 8
1978 10
1979 9
1980 11
1981 7
1982 14
1983 9
1984 12
1985 8
1986 4
1987 9
1988 10
1989 9
1990 8
1991 14
1992 10
1993 9
1994 6
1995 9
1996 5
1997 4
1998 4
1999 6
2000 7
2001 9
2002 8
2003 6
2004 7
2005 4
2006 6
2007 4
2008 4
2009 5
2010 9
2011 10
2012 13
2013 23
2014 12
2015 14
2016 17
2017 16
2018 15
2019 12
2020 20
2021 32
2022 23
2023 28
2024 12

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604 results

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Page 1
Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Chen X, Firulyova M, Manis M, Herz J, Smirnov I, Aladyeva E, Wang C, Bao X, Finn MB, Hu H, Shchukina I, Kim MW, Yuede CM, Kipnis J, Artyomov MN, Ulrich JD, Holtzman DM. Chen X, et al. Among authors: ulrich jd. Nature. 2023 Mar;615(7953):668-677. doi: 10.1038/s41586-023-05788-0. Epub 2023 Mar 8. Nature. 2023. PMID: 36890231 Free PMC article.
ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.
Seo DO, O'Donnell D, Jain N, Ulrich JD, Herz J, Li Y, Lemieux M, Cheng J, Hu H, Serrano JR, Bao X, Franke E, Karlsson M, Meier M, Deng S, Desai C, Dodiya H, Lelwala-Guruge J, Handley SA, Kipnis J, Sisodia SS, Gordon JI, Holtzman DM. Seo DO, et al. Among authors: ulrich jd. Science. 2023 Jan 13;379(6628):eadd1236. doi: 10.1126/science.add1236. Epub 2023 Jan 13. Science. 2023. PMID: 36634180 Free PMC article.
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.
Chen Y, Song S, Parhizkar S, Lord J, Zhu Y, Strickland MR, Wang C, Park J, Tabor GT, Jiang H, Li K, Davis AA, Yuede CM, Colonna M, Ulrich JD, Holtzman DM. Chen Y, et al. Among authors: ulrich jd. Cell. 2024 Jan 18;187(2):428-445.e20. doi: 10.1016/j.cell.2023.11.029. Epub 2023 Dec 11. Cell. 2024. PMID: 38086389
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.
Ulland TK, Song WM, Huang SC, Ulrich JD, Sergushichev A, Beatty WL, Loboda AA, Zhou Y, Cairns NJ, Kambal A, Loginicheva E, Gilfillan S, Cella M, Virgin HW, Unanue ER, Wang Y, Artyomov MN, Holtzman DM, Colonna M. Ulland TK, et al. Among authors: ulrich jd. Cell. 2017 Aug 10;170(4):649-663.e13. doi: 10.1016/j.cell.2017.07.023. Cell. 2017. PMID: 28802038 Free PMC article.
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Gratuze M, Schlachetzki JCM, D'Oliveira Albanus R, Jain N, Novotny B, Brase L, Rodriguez L, Mansel C, Kipnis M, O'Brien S, Pasillas MP, Lee C, Manis M, Colonna M, Harari O, Glass CK, Ulrich JD, Holtzman DM. Gratuze M, et al. Among authors: ulrich jd. Neuron. 2023 Jan 18;111(2):202-219.e7. doi: 10.1016/j.neuron.2022.10.022. Epub 2022 Nov 10. Neuron. 2023. PMID: 36368315 Free PMC article.
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Zhou Y, Song WM, Andhey PS, Swain A, Levy T, Miller KR, Poliani PL, Cominelli M, Grover S, Gilfillan S, Cella M, Ulland TK, Zaitsev K, Miyashita A, Ikeuchi T, Sainouchi M, Kakita A, Bennett DA, Schneider JA, Nichols MR, Beausoleil SA, Ulrich JD, Holtzman DM, Artyomov MN, Colonna M. Zhou Y, et al. Among authors: ulrich jd. Nat Med. 2020 Jan;26(1):131-142. doi: 10.1038/s41591-019-0695-9. Epub 2020 Jan 13. Nat Med. 2020. PMID: 31932797 Free PMC article.
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Litvinchuk A, Suh JH, Guo JL, Lin K, Davis SS, Bien-Ly N, Tycksen E, Tabor GT, Remolina Serrano J, Manis M, Bao X, Lee C, Bosch M, Perez EJ, Yuede CM, Cashikar AG, Ulrich JD, Di Paolo G, Holtzman DM. Litvinchuk A, et al. Among authors: ulrich jd. Neuron. 2024 Feb 7;112(3):384-403.e8. doi: 10.1016/j.neuron.2023.10.023. Epub 2023 Nov 22. Neuron. 2024. PMID: 37995685
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich JD, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner FL, Litvak V, Holtzman DM, Lassmann H, Weiner HL, Ochando J, Haass C, Butovsky O. Krasemann S, et al. Among authors: ulrich jd. Immunity. 2017 Sep 19;47(3):566-581.e9. doi: 10.1016/j.immuni.2017.08.008. Immunity. 2017. PMID: 28930663 Free PMC article.
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia.
Wang C, Xiong M, Gratuze M, Bao X, Shi Y, Andhey PS, Manis M, Schroeder C, Yin Z, Madore C, Butovsky O, Artyomov M, Ulrich JD, Holtzman DM. Wang C, et al. Among authors: ulrich jd. Neuron. 2021 May 19;109(10):1657-1674.e7. doi: 10.1016/j.neuron.2021.03.024. Epub 2021 Apr 7. Neuron. 2021. PMID: 33831349 Free PMC article.
604 results