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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 2
1988 1
1989 2
1990 2
1991 4
1992 3
1993 3
1994 2
1995 6
1996 4
1997 2
1998 3
1999 4
2000 3
2001 2
2002 3
2003 4
2004 5
2005 8
2006 10
2007 10
2008 9
2009 8
2010 10
2011 7
2012 10
2013 8
2014 12
2015 7
2016 9
2017 7
2018 7
2019 10
2020 8
2021 12
2022 8
2023 7
2024 1

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215 results

Results by year

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Page 1
PI3K inhibitors are finally coming of age.
Vanhaesebroeck B, Perry MWD, Brown JR, André F, Okkenhaug K. Vanhaesebroeck B, et al. Nat Rev Drug Discov. 2021 Oct;20(10):741-769. doi: 10.1038/s41573-021-00209-1. Epub 2021 Jun 14. Nat Rev Drug Discov. 2021. PMID: 34127844 Free PMC article. Review.
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration.
Gong GQ, Bilanges B, Allsop B, Masson GR, Roberton V, Askwith T, Oxenford S, Madsen RR, Conduit SE, Bellini D, Fitzek M, Collier M, Najam O, He Z, Wahab B, McLaughlin SH, Chan AWE, Feierberg I, Madin A, Morelli D, Bhamra A, Vinciauskaite V, Anderson KE, Surinova S, Pinotsis N, Lopez-Guadamillas E, Wilcox M, Hooper A, Patel C, Whitehead MA, Bunney TD, Stephens LR, Hawkins PT, Katan M, Yellon DM, Davidson SM, Smith DM, Phillips JB, Angell R, Williams RL, Vanhaesebroeck B. Gong GQ, et al. Among authors: vanhaesebroeck b. Nature. 2023 Jun;618(7963):159-168. doi: 10.1038/s41586-023-05972-2. Epub 2023 May 24. Nature. 2023. PMID: 37225977 Free PMC article.
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Eschweiler S, Ramírez-Suástegui C, Li Y, King E, Chudley L, Thomas J, Wood O, von Witzleben A, Jeffrey D, McCann K, Simon H, Mondal M, Wang A, Dicker M, Lopez-Guadamillas E, Chou TF, Dobbs NA, Essame L, Acton G, Kelly F, Halbert G, Sacco JJ, Schache AG, Shaw R, McCaul JA, Paterson C, Davies JH, Brennan PA, Singh RP, Loadman PM, Wilson W, Hackshaw A, Seumois G, Okkenhaug K, Thomas GJ, Jones TM, Ay F, Friberg G, Kronenberg M, Vanhaesebroeck B, Vijayanand P, Ottensmeier CH. Eschweiler S, et al. Among authors: vanhaesebroeck b. Nature. 2022 May;605(7911):741-746. doi: 10.1038/s41586-022-04685-2. Epub 2022 May 4. Nature. 2022. PMID: 35508656 Free PMC article. Clinical Trial.
PI3K isoforms in cell signalling and vesicle trafficking.
Bilanges B, Posor Y, Vanhaesebroeck B. Bilanges B, et al. Among authors: vanhaesebroeck b. Nat Rev Mol Cell Biol. 2019 Sep;20(9):515-534. doi: 10.1038/s41580-019-0129-z. Nat Rev Mol Cell Biol. 2019. PMID: 31110302 Review.
Cancer-Associated PIK3CA Mutations in Overgrowth Disorders.
Madsen RR, Vanhaesebroeck B, Semple RK. Madsen RR, et al. Among authors: vanhaesebroeck b. Trends Mol Med. 2018 Oct;24(10):856-870. doi: 10.1016/j.molmed.2018.08.003. Epub 2018 Sep 6. Trends Mol Med. 2018. PMID: 30197175 Free PMC article. Review.
Cracking the context-specific PI3K signaling code.
Madsen RR, Vanhaesebroeck B. Madsen RR, et al. Among authors: vanhaesebroeck b. Sci Signal. 2020 Jan 7;13(613):eaay2940. doi: 10.1126/scisignal.aay2940. Sci Signal. 2020. PMID: 31911433 Review.
Phosphoinositide lipids in primary cilia biology.
Conduit SE, Vanhaesebroeck B. Conduit SE, et al. Among authors: vanhaesebroeck b. Biochem J. 2020 Sep 30;477(18):3541-3565. doi: 10.1042/BCJ20200277. Biochem J. 2020. PMID: 32970140 Free PMC article. Review.
PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Kobialka P, Llena J, Deleyto-Seldas N, Munar-Gelabert M, Dengra JA, Villacampa P, Albinyà-Pedrós A, Muixi L, Andrade J, van Splunder H, Angulo-Urarte A, Potente M, Grego-Bessa J, Castillo SD, Vanhaesebroeck B, Efeyan A, Graupera M. Kobialka P, et al. Among authors: vanhaesebroeck b. Sci Signal. 2023 Nov 28;16(813):eadg1913. doi: 10.1126/scisignal.adg1913. Epub 2023 Nov 28. Sci Signal. 2023. PMID: 38015911
Idelalisib inhibits experimental proliferative vitroretinopathy.
Dong L, Han H, Huang X, Ma G, Fang D, Qi H, Han Z, Wang L, Tian J, Vanhaesebroeck B, Zhang G, Zhang S, Lei H. Dong L, et al. Among authors: vanhaesebroeck b. Lab Invest. 2022 Dec;102(12):1296-1303. doi: 10.1038/s41374-022-00822-7. Epub 2022 Jul 19. Lab Invest. 2022. PMID: 35854067 Free article.
215 results