User profiles for "author:Adam Dicker"

Adam Dicker

Thomas Jefferson University
Verified email at jefferson.edu
Cited by 28124

Radiation dose–volume effects in the brain

YR Lawrence, XA Li, I El Naqa, CA Hahn… - International Journal of …, 2010 - Elsevier
We have reviewed the published data regarding radiotherapy (RT)-induced brain injury.
Radiation necrosis appears a median of 1–2 years after RT; however, cognitive decline …

Comparative analysis of prostate‐specific antigen free survival outcomes for patients with low, intermediate and high risk prostate cancer treatment by radical therapy …

P Grimm, I Billiet, D Bostwick, AP Dicker… - BJU …, 2012 - Wiley Online Library
What's known on the subject? and What does the study add? Very few comparative studies
to date evaluate the results of treatment options for prostate cancer using the most sensitive …

Zebrafish: an emerging model system for human disease and drug discovery

G Kari, U Rodeck, AP Dicker - Clinical Pharmacology & …, 2007 - Wiley Online Library
In vivo studies represent an essential step in drug development and currently rely largely on
mice, yet limitations of mammalian models motivated the search for complementary …

American Society of Clinical Oncology statement: a conceptual framework to assess the value of cancer treatment options

LE Schnipper, NE Davidson, DS Wollins… - Journal of Clinical …, 2015 - ascopubs.org
Health care costs in the United States present a major challenge to the national economic
well being. The Centers for Medicare and Medicaid Services (CMS) has projected that US …

Outcomes of observation vs stereotactic ablative radiation for oligometastatic prostate cancer: the ORIOLE phase 2 randomized clinical trial

R Phillips, WY Shi, M Deek, N Radwan, SJ Lim… - JAMA …, 2020 - jamanetwork.com
Importance Complete metastatic ablation of oligometastatic prostate cancer may provide an
alternative to early initiation of androgen deprivation therapy (ADT). Objective To determine …

Microsurgical inguinal varicocelectomy with delivery of the testis: an artery and lymphatic sparing technique

M Goldstein, BR Gilbert, AP Dicker, J Dwosh… - The Journal of …, 1992 - Elsevier
Conventional techniques of varicocele repair are associated with substantial risks of
hydrocele formation, ligation of the testicular artery, and varicocele recurrence. We describe …

[PDF][PDF] Updating the American Society of Clinical Oncology value framework: revisions and reflections in response to comments received

LE Schnipper, NE Davidson… - Journal of Clinical …, 2016 - populationmedicine.org
The mission of American Society of Clinical Oncology (ASCO) is to conquer cancer through
research, education, and promotion of the highest quality patient care. Toward fulfillment of …

[HTML][HTML] Federated learning enables big data for rare cancer boundary detection

S Pati, U Baid, B Edwards, M Sheller, SH Wang… - Nature …, 2022 - nature.com
Although machine learning (ML) has shown promise across disciplines, out-of-sample
generalizability is concerning. This is currently addressed by sharing multi-site data, but …

Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer

JJ Farrell, H Elsaleh, M Garcia, R Lai, A Ammar… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: The human equilibrative nucleoside transporter (hENT1) protein
transports gemcitabine into cells. Small retrospective studies in pancreatic cancer suggest …

Dihydrofolate reductase as a therapeutic target

BI Schweitzer, AP Dicker, JR Bertino - The FASEB journal, 1990 - Wiley Online Library
The folate antagonists are an important class of therapeutic compounds, as evidenced by
their use as antiinfective, antineoplastic, and antiinflammatory drugs. Thus far, all of the …