6-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications

PL Jager, R Chirakal, CJ Marriott… - Journal of nuclear …, 2008 - Soc Nuclear Med
In recent years, 6-l-18F-fluorodihydroxyphenylalanine (18F-DOPA) PET has emerged as a
new diagnostic tool for the imaging of neuroendocrine tumors. This application is based on …

Antibody positron emission tomography imaging in anticancer drug development

LE Lamberts, SP Williams… - Journal of Clinical …, 2015 - ascopubs.org
More than 50 monoclonal antibodies (mAbs), including several antibody–drug conjugates,
are in advanced clinical development, forming an important part of the many molecularly …

Theranostics using antibodies and antibody-related therapeutics

KL Moek, D Giesen, IC Kok, DJA de Groot… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In theranostics, radiolabeled compounds are used to determine a treatment strategy by
combining therapeutics and diagnostics in the same agent. Monoclonal antibodies (mAbs) …

89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

F Bensch, EL van der Veen, MN Lub-de Hooge… - Nature medicine, 2018 - nature.com
Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade is effective in a subset of
patients with several tumor types, but predicting patient benefit using approved diagnostics …

In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft

WB Nagengast, EG De Vries, GA Hospers… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Vascular endothelial growth factor (VEGF), released by tumor cells, is an important growth
factor in tumor angiogenesis. The humanized monoclonal antibody bevacizumab blocks …

[HTML][HTML] Whole-body CD8+ T cell visualization before and during cancer immunotherapy: a phase 1/2 trial

L Kist de Ruijter, PP van de Donk… - Nature Medicine, 2022 - nature.com
Immune checkpoint inhibitors (ICIs), by reinvigorating CD8+ T cell mediated immunity, have
revolutionized cancer therapy. Yet, the systemic CD8+ T cell distribution, a potential …

[PDF][PDF] Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission …

KP Koopmans, OC Neels, IP Kema… - Journal of clinical …, 2008 - researchgate.net
Improved Staging of Patients With Carcinoid and Islet Cell Tumors With 18F-Dihydroxy-Phenyl-Alanine
and 11C-5-Hydroxy-Tryptophan Page 1 Improved Staging of Patients With Carcinoid and Islet …

89Zr-bevacizumab PET imaging in primary breast cancer

SBM Gaykema, AH Brouwers… - Journal of nuclear …, 2013 - Soc Nuclear Med
Vascular endothelial growth factor (VEGF)-A is overexpressed in most malignant and
premalignant breast lesions. VEGF-A can be visualized noninvasively with PET imaging and …

6-[F-18]Fluoro-l-Dihydroxyphenylalanine Positron Emission Tomography Is Superior to Conventional Imaging with 123I-Metaiodobenzylguanidine Scintigraphy …

HB Fiebrich, AH Brouwers, MN Kerstens… - The Journal of …, 2009 - academic.oup.com
Context: Catecholamine excess is rare, but symptoms may be life threatening. Objective:
The objective of the study was to investigate the sensitivity of 6-[F-18] fluoro-l …

89Zr-bevacizumab PET visualizes heterogeneous tracer accumulation in tumor lesions of renal cell carcinoma patients and differential effects of antiangiogenic …

SF Oosting, AH Brouwers, SC van Es… - Journal of Nuclear …, 2015 - Soc Nuclear Med
No validated predictive biomarkers for antiangiogenic treatment of metastatic renal cell
carcinoma (mRCC) exist. Tumor vascular endothelial growth factor A (VEGF-A) level may be …