Resistance mechanisms to anti-HER2 therapies in HER2-positive breast cancer: Current knowledge, new research directions and therapeutic perspectives

C Vernieri, M Milano, M Brambilla, A Mennitto… - Critical reviews in …, 2019 - Elsevier
HER2-positive breast cancer (HER2+ BC) represents 15–20% of all BCs. In the last two
decades, the introduction of monoclonal antibodies (MoAbs), tyrosine kinase inhibitors …

[HTML][HTML] Prognostic value of diffuse versus intestinal histotype in patients with gastric cancer: a systematic review and meta-analysis

F Petrelli, R Berenato, L Turati, A Mennitto… - Journal of …, 2017 - ncbi.nlm.nih.gov
Background There are two distinct types of gastric carcinoma (GC), intestinal, more
frequently sporadic and linked to environmental factors, and diffuse (undifferentiated) that is …

[HTML][HTML] Predictive biomarkers of response to immunotherapy in metastatic renal cell cancer

A Raimondi, P Sepe, E Zattarin, A Mennitto… - Frontiers in …, 2020 - frontiersin.org
Introduction In the last decades, the therapeutic decision-making approach to metastatic
renal cell cancer (mRCC) has dramatically changed thanks to the introduction in the …

Heterogeneity of acquired resistance to anti-EGFR monoclonal antibodies in patients with metastatic colorectal cancer

F Pietrantonio, C Vernieri, G Siravegna, A Mennitto… - Clinical cancer …, 2017 - AACR
Abstract Purpose: Even if RAS-BRAF wild-type and HER2/MET–negative metastatic
colorectal cancer (mCRC) patients frequently respond to anti-EGFR mAbs, acquired …

Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic …

R Moretto, C Cremolini, D Rossini, F Pietrantonio… - The …, 2016 - academic.oup.com
Introduction. Right-and left-sided colorectal cancers (CRCs) differ in clinical and molecular
characteristics. Some retrospective analyses suggested that patients with right-sided tumors …

[HTML][HTML] Optimal sequencing and predictive biomarkers in patients with advanced prostate cancer

C Cattrini, R España, A Mennitto, M Bersanelli… - Cancers, 2021 - mdpi.com
Simple Summary Several strategies have demonstrated the ability to improve the survival of
patients with both metastatic and nonmetastatic prostate cancer. The old backbone of …

[HTML][HTML] Apalutamide, darolutamide and enzalutamide for nonmetastatic castration-resistant prostate cancer (nmCRPC): a critical review

C Cattrini, O Caffo, U De Giorgi, A Mennitto, A Gennari… - Cancers, 2022 - mdpi.com
Simple Summary Apalutamide, darolutamide and enzalutamide are androgen-receptor
signaling inhibitors proved to be useful in patients with nonmetastatic castration-resistant …

[HTML][HTML] The neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict efficacy of platinum-based chemotherapy in patients with metastatic triple negative …

C Vernieri, A Mennitto, M Prisciandaro, V Huber… - Scientific reports, 2018 - nature.com
Platinum salts are active against metastatic triple negative breast cancer (mTNBC), and
biomarkers to predict their effectiveness are urgently needed. In recent years, the neutrophil …

[HTML][HTML] Insulin/IGF axis in breast cancer: clinical evidence and translational insights

F Biello, F Platini, F D'avanzo, C Cattrini, A Mennitto… - Biomolecules, 2021 - mdpi.com
Background: Breast cancer (BC) is the most common neoplasm in women. Many clinical and
preclinical studies investigated the possible relationship between host metabolism and BC …

Single-Agent Panitumumab in Frail Elderly Patients With Advanced RAS and BRAF Wild-Type Colorectal Cancer: Challenging Drug Label to Light Up New Hope

F Pietrantonio, C Cremolini, G Aprile, S Lonardi… - The …, 2015 - academic.oup.com
Background. No prospective trials have specifically addressed the efficacy and safety of
panitumumab in elderly patients with metastatic colorectal cancer (CRC). We aimed at …