Resistance mechanisms to anti-HER2 therapies in HER2-positive breast cancer: Current knowledge, new research directions and therapeutic perspectives
C Vernieri, M Milano, M Brambilla, A Mennitto… - Critical reviews in …, 2019 - Elsevier
HER2-positive breast cancer (HER2+ BC) represents 15–20% of all BCs. In the last two
decades, the introduction of monoclonal antibodies (MoAbs), tyrosine kinase inhibitors …
decades, the introduction of monoclonal antibodies (MoAbs), tyrosine kinase inhibitors …
[HTML][HTML] Prognostic value of diffuse versus intestinal histotype in patients with gastric cancer: a systematic review and meta-analysis
F Petrelli, R Berenato, L Turati, A Mennitto… - Journal of …, 2017 - ncbi.nlm.nih.gov
Background There are two distinct types of gastric carcinoma (GC), intestinal, more
frequently sporadic and linked to environmental factors, and diffuse (undifferentiated) that is …
frequently sporadic and linked to environmental factors, and diffuse (undifferentiated) that is …
[HTML][HTML] Predictive biomarkers of response to immunotherapy in metastatic renal cell cancer
A Raimondi, P Sepe, E Zattarin, A Mennitto… - Frontiers in …, 2020 - frontiersin.org
Introduction In the last decades, the therapeutic decision-making approach to metastatic
renal cell cancer (mRCC) has dramatically changed thanks to the introduction in the …
renal cell cancer (mRCC) has dramatically changed thanks to the introduction in the …
Heterogeneity of acquired resistance to anti-EGFR monoclonal antibodies in patients with metastatic colorectal cancer
F Pietrantonio, C Vernieri, G Siravegna, A Mennitto… - Clinical cancer …, 2017 - AACR
Abstract Purpose: Even if RAS-BRAF wild-type and HER2/MET–negative metastatic
colorectal cancer (mCRC) patients frequently respond to anti-EGFR mAbs, acquired …
colorectal cancer (mCRC) patients frequently respond to anti-EGFR mAbs, acquired …
Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic …
Introduction. Right-and left-sided colorectal cancers (CRCs) differ in clinical and molecular
characteristics. Some retrospective analyses suggested that patients with right-sided tumors …
characteristics. Some retrospective analyses suggested that patients with right-sided tumors …
[HTML][HTML] Optimal sequencing and predictive biomarkers in patients with advanced prostate cancer
C Cattrini, R España, A Mennitto, M Bersanelli… - Cancers, 2021 - mdpi.com
Simple Summary Several strategies have demonstrated the ability to improve the survival of
patients with both metastatic and nonmetastatic prostate cancer. The old backbone of …
patients with both metastatic and nonmetastatic prostate cancer. The old backbone of …
[HTML][HTML] Apalutamide, darolutamide and enzalutamide for nonmetastatic castration-resistant prostate cancer (nmCRPC): a critical review
Simple Summary Apalutamide, darolutamide and enzalutamide are androgen-receptor
signaling inhibitors proved to be useful in patients with nonmetastatic castration-resistant …
signaling inhibitors proved to be useful in patients with nonmetastatic castration-resistant …
[HTML][HTML] The neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict efficacy of platinum-based chemotherapy in patients with metastatic triple negative …
C Vernieri, A Mennitto, M Prisciandaro, V Huber… - Scientific reports, 2018 - nature.com
Platinum salts are active against metastatic triple negative breast cancer (mTNBC), and
biomarkers to predict their effectiveness are urgently needed. In recent years, the neutrophil …
biomarkers to predict their effectiveness are urgently needed. In recent years, the neutrophil …
[HTML][HTML] Insulin/IGF axis in breast cancer: clinical evidence and translational insights
F Biello, F Platini, F D'avanzo, C Cattrini, A Mennitto… - Biomolecules, 2021 - mdpi.com
Background: Breast cancer (BC) is the most common neoplasm in women. Many clinical and
preclinical studies investigated the possible relationship between host metabolism and BC …
preclinical studies investigated the possible relationship between host metabolism and BC …
Single-Agent Panitumumab in Frail Elderly Patients With Advanced RAS and BRAF Wild-Type Colorectal Cancer: Challenging Drug Label to Light Up New Hope
Background. No prospective trials have specifically addressed the efficacy and safety of
panitumumab in elderly patients with metastatic colorectal cancer (CRC). We aimed at …
panitumumab in elderly patients with metastatic colorectal cancer (CRC). We aimed at …