User profiles for "author:Alessia Volpe"

Alessia Volpe

Memorial Sloan Kettering Cancer Center
Verified email at mskcc.org
Cited by 517

Simultaneous quantitative imaging of two PET radiotracers via the detection of positron–electron annihilation and prompt gamma emissions

EC Pratt, A Lopez-Montes, A Volpe… - Nature Biomedical …, 2023 - nature.com
In conventional positron emission tomography (PET), only one radiotracer can be imaged at
a time, because all PET isotopes produce the same two 511 keV annihilation photons. Here …

[HTML][HTML] Cousins at work: how combining medical with optical imaging enhances in vivo cell tracking

A Volpe, E Kurtys, GO Fruhwirth - … journal of biochemistry & cell biology, 2018 - Elsevier
Microscopy and medical imaging are related in their exploitation of electromagnetic waves,
but were developed to satisfy differing needs, namely to observe small objects or to look …

[HTML][HTML] Imaging cellular immunotherapies and immune cell biomarkers: from preclinical studies to patients

A Volpe, PS Adusumilli, H Schöder… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Cellular immunotherapies have emerged as a successful therapeutic approach to fight a
wide range of human diseases, including cancer. However, responses are limited to few …

[HTML][HTML] In vivo PET tracking of 89Zr-labeled Vγ9Vδ2 T cells to mouse xenograft breast tumors activated with liposomal alendronate

F Man, L Lim, A Volpe, A Gabizon, H Shmeeda… - Molecular Therapy, 2019 - cell.com
Gammadelta T (γδ-T) cells are strong candidates for adoptive immunotherapy in oncology
due to their cytotoxicity, ease of expansion, and favorable safety profile. The development of …

Exploiting the Metal-Chelating Properties of the Drug Cargo for In Vivo Positron Emission Tomography Imaging of Liposomal Nanomedicines

S Edmonds, A Volpe, H Shmeeda… - ACS …, 2016 - ACS Publications
The clinical value of current and future nanomedicines can be improved by introducing
patient selection strategies based on noninvasive sensitive whole-body imaging techniques …

[HTML][HTML] Spatiotemporal PET imaging reveals differences in CAR-T tumor retention in triple-negative breast cancer models

A Volpe, C Lang, L Lim, F Man, E Kurtys… - Molecular Therapy, 2020 - cell.com
Chimeric antigen receptor T cell therapy (CAR-T) has been rolled out as a new treatment for
hematological malignancies. For solid tumor treatment, CAR-T has been disappointing so …

PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling

AA Khan, F Man, FN Faruqu, J Kim… - Bioconjugate …, 2022 - ACS Publications
Exosomes or small extracellular vesicles (sEVs) are increasingly gaining attention for their
potential as drug delivery systems and biomarkers of disease. Therefore, it is important to …

[HTML][HTML] Supporting global initiatives on climate change: The EPO's “Y02-Y04S” tagging scheme

S Angelucci, FJ Hurtado-Albir, A Volpe - World Patent Information, 2018 - Elsevier
The EPO has developed a dedicated classification scheme for climate change mitigation
technologies (CCMTs), where relevant patent publications are “tagged” and classified into a …

[HTML][HTML] Applications of nuclear-based imaging in gene and cell therapy: Probe considerations

A Volpe, NVK Pillarsetty, JS Lewis… - Molecular Therapy …, 2021 - cell.com
Several types of gene-and cell-based therapeutics are now emerging in the cancer
immunotherapy, transplantation, and regenerative medicine landscapes. Radionuclear …

[HTML][HTML] Radiolabelling of Polyclonally Expanded Human Regulatory T Cells (Treg) with 89Zr-oxine for Medium-Term In Vivo Cell Tracking

J Jacob, A Volpe, Q Peng, RI Lechler, LA Smyth… - Molecules, 2023 - mdpi.com
Regulatory T cells (Tregs) are a promising candidate cell therapy to treat autoimmune
diseases and aid the longevity of transplanted solid organs. Despite increasing numbers of …