[HTML][HTML] The role of PD-L1 expression as a predictive biomarker: an analysis of all US Food and Drug Administration (FDA) approvals of immune checkpoint inhibitors
AA Davis, VG Patel - Journal for immunotherapy of cancer, 2019 - Springer
The development of immune checkpoint inhibitors has changed the treatment paradigm for
advanced cancers across many tumor types. Despite encouraging and sometimes durable …
advanced cancers across many tumor types. Despite encouraging and sometimes durable …
The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper
M Cristofanilli, JY Pierga, J Reuben… - Critical reviews in …, 2019 - Elsevier
Background The heterogeneity of metastatic breast cancer (MBC) necessitates novel
biomarkers allowing stratification of patients for treatment selection and drug development …
biomarkers allowing stratification of patients for treatment selection and drug development …
[HTML][HTML] Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling
YK Chae, SY Chung, AA Davis, BA Carneiro… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Adenoid cystic carcinoma (ACC) is a rare cancer with high potential for recurrence and
metastasis. Efficacy of current treatment options, particularly for advanced disease, is very …
metastasis. Efficacy of current treatment options, particularly for advanced disease, is very …
[PDF][PDF] Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells
X Qian, Q Shen, SK Goderie, W He, A Capela… - Neuron, 2000 - cell.com
Multipotent stem cells that generate both neurons and glia are widespread components of
the early neuroepithelium. During CNS development, neurogenesis largely precedes …
the early neuroepithelium. During CNS development, neurogenesis largely precedes …
A self-renewing multipotential stem cell in embryonic rat cerebral cortex
AA Davis, S Temple - Nature, 1994 - nature.com
NEUROECTODERM cells in the cortical ventricular zone generate many diverse cell types,
maintain the ventricular zone during embryonic life and create another germinal layer, the …
maintain the ventricular zone during embryonic life and create another germinal layer, the …
[PDF][PDF] FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells
X Qian, AA Davis, SK Goderie, S Temple - Neuron, 1997 - cell.com
The embryonic cerebral cortex contains a population of stem-like founder cells capable of
generating large, mixed clones of neurons and glia in vitro. We report that the default state of …
generating large, mixed clones of neurons and glia in vitro. We report that the default state of …
[HTML][HTML] ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer
R Taftaf, X Liu, S Singh, Y Jia, NK Dashzeveg… - Nature …, 2021 - nature.com
Circulating tumor cell (CTC) clusters mediate metastasis at a higher efficiency and are
associated with lower overall survival in breast cancer compared to single cells. Combining …
associated with lower overall survival in breast cancer compared to single cells. Combining …
Concordance of genomic alterations by next-generation sequencing in tumor tissue versus circulating tumor DNA in breast cancer
YK Chae, AA Davis, S Jain, C Santa-Maria… - Molecular cancer …, 2017 - AACR
While identifying genomic alterations in tumor tissue is the current gold-standard technique
for molecular profiling, circulating tumor DNA (ctDNA) represents a noninvasive method of …
for molecular profiling, circulating tumor DNA (ctDNA) represents a noninvasive method of …
Biomarkers for PD-1/PD-L1 blockade therapy in non–small-cell lung cancer: Is PD-L1 expression a good marker for patient selection?
Immunotherapy has emerged as a promising treatment modality in cancer therapy. With
improved understanding of how to tip the balance of immune homeostasis, novel …
improved understanding of how to tip the balance of immune homeostasis, novel …
Clinical implications of circulating tumor DNA tumor mutational burden (ctDNA TMB) in non‐small cell lung cancer
Background Tissue tumor mutational burden (TMB) has emerged as a potential biomarker
predicting response to anti‐programmed cell death‐1 protein receptor (PD‐1)/programmed …
predicting response to anti‐programmed cell death‐1 protein receptor (PD‐1)/programmed …