[HTML][HTML] The role of PD-L1 expression as a predictive biomarker: an analysis of all US Food and Drug Administration (FDA) approvals of immune checkpoint inhibitors

AA Davis, VG Patel - Journal for immunotherapy of cancer, 2019 - Springer
The development of immune checkpoint inhibitors has changed the treatment paradigm for
advanced cancers across many tumor types. Despite encouraging and sometimes durable …

The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper

M Cristofanilli, JY Pierga, J Reuben… - Critical reviews in …, 2019 - Elsevier
Background The heterogeneity of metastatic breast cancer (MBC) necessitates novel
biomarkers allowing stratification of patients for treatment selection and drug development …

[HTML][HTML] Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling

YK Chae, SY Chung, AA Davis, BA Carneiro… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Adenoid cystic carcinoma (ACC) is a rare cancer with high potential for recurrence and
metastasis. Efficacy of current treatment options, particularly for advanced disease, is very …

[PDF][PDF] Timing of CNS cell generation: a programmed sequence of neuron and glial cell production from isolated murine cortical stem cells

X Qian, Q Shen, SK Goderie, W He, A Capela… - Neuron, 2000 - cell.com
Multipotent stem cells that generate both neurons and glia are widespread components of
the early neuroepithelium. During CNS development, neurogenesis largely precedes …

A self-renewing multipotential stem cell in embryonic rat cerebral cortex

AA Davis, S Temple - Nature, 1994 - nature.com
NEUROECTODERM cells in the cortical ventricular zone generate many diverse cell types,
maintain the ventricular zone during embryonic life and create another germinal layer, the …

[PDF][PDF] FGF2 concentration regulates the generation of neurons and glia from multipotent cortical stem cells

X Qian, AA Davis, SK Goderie, S Temple - Neuron, 1997 - cell.com
The embryonic cerebral cortex contains a population of stem-like founder cells capable of
generating large, mixed clones of neurons and glia in vitro. We report that the default state of …

[HTML][HTML] ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer

R Taftaf, X Liu, S Singh, Y Jia, NK Dashzeveg… - Nature …, 2021 - nature.com
Circulating tumor cell (CTC) clusters mediate metastasis at a higher efficiency and are
associated with lower overall survival in breast cancer compared to single cells. Combining …

Concordance of genomic alterations by next-generation sequencing in tumor tissue versus circulating tumor DNA in breast cancer

YK Chae, AA Davis, S Jain, C Santa-Maria… - Molecular cancer …, 2017 - AACR
While identifying genomic alterations in tumor tissue is the current gold-standard technique
for molecular profiling, circulating tumor DNA (ctDNA) represents a noninvasive method of …

Biomarkers for PD-1/PD-L1 blockade therapy in non–small-cell lung cancer: Is PD-L1 expression a good marker for patient selection?

YK Chae, A Pan, AA Davis, K Raparia, NA Mohindra… - Clinical lung cancer, 2016 - Elsevier
Immunotherapy has emerged as a promising treatment modality in cancer therapy. With
improved understanding of how to tip the balance of immune homeostasis, novel …

Clinical implications of circulating tumor DNA tumor mutational burden (ctDNA TMB) in non‐small cell lung cancer

YK Chae, AA Davis, S Agte, A Pan, NI Simon… - The …, 2019 - academic.oup.com
Background Tissue tumor mutational burden (TMB) has emerged as a potential biomarker
predicting response to anti‐programmed cell death‐1 protein receptor (PD‐1)/programmed …