Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

Statin-Associated Autoimmune Myopathy | NEJM Skip to main content NEJM Group Follow Us
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Inflammatory myopathies, collectively known as myositis, are heterogeneous disorders
characterised by muscle inflammation, and frequently accompanied by extramuscular …

We have characterized the phosphorylation of the glutamate receptor subunit GluR1, using
biochemical and electrophysiological techniques. GluR1 is phosphorylated on multiple sites …

Objective In addition to inducing a self‐limited myopathy, statin use is associated with an
immune‐mediated necrotizing myopathy (IMNM), with autoantibodies that recognize∼ 200 …

Objective Myofiber necrosis without prominent inflammation is a nonspecific finding in
patients with dystrophies and toxic or immune‐mediated myopathies. However, the etiology …

Modulation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic Acid (AMPA) receptors in
the brain by protein phosphorylation may play a crucial role in the regulation of synaptic …

Objective Since dermatomyositis (DM) is associated with an increased risk of malignancy,
accurate identification of patients likely to harbor cancers is important. Using …

Among the idiopathic inflammatory myopathies (IIMs), immune-mediated necrotizing
myopathies (IMNMs) have been identified as important and separate entities during the past …

Abstract Objective Autoantibodies recognizing 3‐hydroxy‐3‐methylglutaryl‐coenzyme A
reductase (HMGCR) are found in patients with statin‐associated immune‐mediated …