User profiles for "author:Angela Vasaturo"
Angela VasaturoCordeliers Research Center Verified email at crc.jussieu.fr Cited by 4481 |
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou… - The Lancet, 2018 - thelancet.com
Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …
improved. A robust immune score quantification is needed to introduce immune parameters …
[HTML][HTML] Clinical implications of co-inhibitory molecule expression in the tumor microenvironment for DC vaccination: a game of stop and go
A Vasaturo, S Di Blasio, DGA Peeters… - Frontiers in …, 2013 - frontiersin.org
The aim of therapeutic dendritic cell (DC) vaccines in cancer immunotherapy is to activate
cytotoxic T cells to recognize and attack the tumor. T cell activation requires the interaction of …
cytotoxic T cells to recognize and attack the tumor. T cell activation requires the interaction of …
The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis
B Mlecnik, G Bindea, A Kirilovsky, HK Angell… - Science translational …, 2016 - science.org
Although distant metastases account for most of the deaths in cancer patients, fundamental
questions regarding mechanisms that promote or inhibit metastasis remain unanswered. We …
questions regarding mechanisms that promote or inhibit metastasis remain unanswered. We …
[PDF][PDF] Evolution of metastases in space and time under immune selection
We examined how the immune microenvironment molds tumor evolution at different
metastatic organs in a longitudinal dataset of colorectal cancer. Through multiplexed …
metastatic organs in a longitudinal dataset of colorectal cancer. Through multiplexed …
Immune evasion before tumour invasion in early lung squamous carcinogenesis
Early detection and treatment are critical for improving the outcome of patients with cancer.
Understanding the largely uncharted biology of carcinogenesis requires deciphering …
Understanding the largely uncharted biology of carcinogenesis requires deciphering …
Comprehensive intrametastatic immune quantification and major impact of immunoscore on survival
B Mlecnik, M Van den Eynde, G Bindea… - JNCI: Journal of the …, 2018 - academic.oup.com
Background This study assesses how the metastatic immune landscape is impacting the
response to treatment and the outcome of colorectal cancer (CRC) patients. Methods …
response to treatment and the outcome of colorectal cancer (CRC) patients. Methods …
[PDF][PDF] The link between the multiverse of immune microenvironments in metastases and the survival of colorectal cancer patients
M Van den Eynde, B Mlecnik, G Bindea, T Fredriksen… - Cancer cell, 2018 - cell.com
Treatment of metastatic colorectal cancer is based upon the assumption that metastases are
homogeneous within a patient. We quantified immune cell types of 603 whole-slide …
homogeneous within a patient. We quantified immune cell types of 603 whole-slide …
Two-photon laser-generated microtracks in 3D collagen lattices: principles of MMP-dependent and-independent collective cancer cell invasion
O Ilina, GJ Bakker, A Vasaturo, RM Hoffman… - Physical …, 2011 - iopscience.iop.org
Cancer invasion into an extracellular matrix (ECM) results from a biophysical reciprocal
interplay between the expanding cancer lesion and tissue barriers imposed by the adjacent …
interplay between the expanding cancer lesion and tissue barriers imposed by the adjacent …
Lysosomal accumulation of gliadin p31–43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARγ downregulation in intestinal epithelial cells …
A Luciani, VR Villella, A Vasaturo, I Giardino… - Gut, 2010 - gut.bmj.com
Background An unresolved question in coeliac disease is to understand how some toxic
gliadin peptides, in particular p31–43, can initiate an innate response and lead to tissue …
gliadin peptides, in particular p31–43, can initiate an innate response and lead to tissue …
SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation
A Luciani, VR Villella, A Vasaturo, I Giardino… - The Journal of …, 2009 - journals.aai.org
Cystic fibrosis (CF) is a monogenic disease caused by mutations in the CF transmembrane
conductance regulator (CFTR) gene. CF is characterized by chronic bacterial lung infections …
conductance regulator (CFTR) gene. CF is characterized by chronic bacterial lung infections …