User profiles for "author:Annacarolina Da Silva"
Annacarolina da SilvaWeill Cornell Medicine/NewYork Presbyterian Hospital Verified email at med.cornell.edu Cited by 3682 |
Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine
AJ Aguirre, JA Nowak, ND Camarda, RA Moffitt… - Cancer discovery, 2018 - AACR
Clinically relevant subtypes exist for pancreatic ductal adenocarcinoma (PDAC), but
molecular characterization is not yet standard in clinical care. We implemented a biopsy …
molecular characterization is not yet standard in clinical care. We implemented a biopsy …
Fusobacterium nucleatumin Colorectal Carcinoma Tissue According to Tumor Location
OBJECTIVES: Evidence suggests a possible role ofFusobacterium nucleatumin colorectal
carcinogenesis, especially in right-sided proximal colorectum. Considering a change in …
carcinogenesis, especially in right-sided proximal colorectum. Considering a change in …
Tumour CD274 (PD-L1) expression and T cells in colorectal cancer
Y Masugi, R Nishihara, J Yang, K Mima, A Da Silva… - Gut, 2017 - gut.bmj.com
Objective Evidence suggests that CD274 (programmed death-ligand 1, B7-H1) immune
checkpoint ligand repress antitumour immunity through its interaction with the PDCD1 …
checkpoint ligand repress antitumour immunity through its interaction with the PDCD1 …
Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer
MB Yurgelun, AB Chittenden, V Morales-Oyarvide… - Genetics in …, 2019 - nature.com
Purpose Germline variants in double-strand DNA damage repair (dsDDR) genes (eg,
BRCA1/2) predispose to pancreatic adenocarcinoma (PDAC) and may predict sensitivity to …
BRCA1/2) predispose to pancreatic adenocarcinoma (PDAC) and may predict sensitivity to …
Leukocyte heterogeneity in pancreatic ductal adenocarcinoma: phenotypic and spatial features associated with clinical outcome
SM Liudahl, CB Betts, S Sivagnanam… - Cancer discovery, 2021 - AACR
Immunotherapies targeting aspects of T cell functionality are efficacious in many solid
tumors, but pancreatic ductal adenocarcinoma (PDAC) remains refractory to these …
tumors, but pancreatic ductal adenocarcinoma (PDAC) remains refractory to these …
Association of alterations in main driver genes with outcomes of patients with resected pancreatic ductal adenocarcinoma
ZR Qian, DA Rubinson, JA Nowak… - JAMA …, 2018 - jamanetwork.com
Importance Although patients with resected pancreatic adenocarcinoma are at high risk for
disease recurrence, few biomarkers are available to inform patient outcomes. Objective To …
disease recurrence, few biomarkers are available to inform patient outcomes. Objective To …
The prognostic role of macrophage polarization in the colorectal cancer microenvironment
Macrophages are among the most common cells in the colorectal cancer microenvironment,
but their prognostic significance is incompletely understood. Using multiplexed …
but their prognostic significance is incompletely understood. Using multiplexed …
Dietary patterns and risk of colorectal cancer: analysis by tumor location and molecular subtypes
Background & Aims Western and prudent dietary patterns have been associated with higher
and lower risks of colorectal cancer (CRC), respectively. However, little is known about the …
and lower risks of colorectal cancer (CRC), respectively. However, little is known about the …
Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors
P Cejas, Y Drier, KMA Dreijerink, LAA Brosens… - Nature medicine, 2019 - nature.com
Most pancreatic neuroendocrine tumors (PNETs) do not produce excess hormones and are
therefore considered 'non-functional',–. As clinical behaviors vary widely and distant …
therefore considered 'non-functional',–. As clinical behaviors vary widely and distant …
Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status
The presence of Fusobacterium nucleatum (F. nucleatum) in colorectal carcinoma tissue has
been associated with microsatellite instability (MSI), lower-level T-cell infiltrates, and poor …
been associated with microsatellite instability (MSI), lower-level T-cell infiltrates, and poor …