Serum therapy remains the only specific treatment against envenoming, but anti-venoms are
still prepared by fragmentation of polyclonal antibodies isolated from hyper-immunized …

Breast cancer metastasis is a leading cause of death by malignancy in women worldwide.
Efforts are being made to further characterize the rate-limiting steps of cancer metastasis, ie …

Background Breast cancer is a heterogeneous disease that is not totally eradicated by
current therapies. The classification of breast tumors into distinct molecular subtypes by …

Metastasis, a fatal complication of breast cancer, does not fully benefit from available
therapies. In this study, we investigated whether ATIP3, the major product of 8p22 MTUS1 …

Toxoplasmosis is a major public health problem and the development of a human vaccine is
of high priority. Efficient vaccination against Toxoplasma gondii requires both a mucosal and …

abstract Recombinant antibody single-chain variable fragments (scFv) are difficult to purify
homogeneously from a protein complex mixture. The most effective, specific and fastest …

The ARF tumor suppressor signals through p53 and other poorly defined anti-proliferative
pathways to block carcinogenesis. In a search for new regulators of ARF signaling, we …

There is an urgent need for alternative therapies targeting human dendritic cells (DCs) that
could reverse inflammatory syndromes in many autoimmune and inflammatory diseases and …

The Alternative Reading Frame (ARF) protein suppresses tumorigenesis through p53-
dependent and p53-independent pathways. Most of ARF's anti-proliferative activity is …

Androctonus australis is primarily involved in envenomations in North Africa, notably in
Tunisia and Algeria, and constitutes a significant public health problem in this region. The …