[PDF][PDF] A specific gut microbiota dysbiosis of type 2 diabetic mice induces GLP-1 resistance through an enteric NO-dependent and gut-brain axis mechanism
E Grasset, A Puel, J Charpentier, X Collet… - Cell metabolism, 2017 - cell.com
Summary Glucagon-like peptide-1 (GLP-1)-based therapies control glycemia in type 2
diabetic (T2D) patients. However, in some patients the treatment must be discontinued …
diabetic (T2D) patients. However, in some patients the treatment must be discontinued …
[HTML][HTML] Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies
Y Ashraf, H Mansouri, V Laurent-Matha… - … for Immunotherapy of …, 2019 - Springer
Background Triple-negative breast cancer (TNBC) treatment is currently restricted to
chemotherapy. Hence, tumor-specific molecular targets and/or alternative therapeutic …
chemotherapy. Hence, tumor-specific molecular targets and/or alternative therapeutic …
[HTML][HTML] Triggering the adaptive immune system with commensal gut bacteria protects against insulin resistance and dysglycemia
C Pomié, V Blasco-Baque, P Klopp, S Nicolas… - Molecular …, 2016 - Elsevier
Objective To demonstrate that glycemia and insulin resistance are controlled by a
mechanism involving the adaptive immune system and gut microbiota crosstalk. Methods …
mechanism involving the adaptive immune system and gut microbiota crosstalk. Methods …
Liraglutide targets the gut microbiota and the intestinal immune system to regulate insulin secretion
J Charpentier, F Briand, B Lelouvier, F Servant… - Acta Diabetologica, 2021 - Springer
Aims Liraglutide controls type 2 diabetes (T2D) and inflammation. Gut microbiota regulates
the immune system and causes at least in part type 2 diabetes. We here evaluated whether …
the immune system and causes at least in part type 2 diabetes. We here evaluated whether …
Gut microbiota dysbiosis of type 2 diabetic mice impairs the intestinal daily rhythms of GLP-1 sensitivity
E Grasset, A Puel, J Charpentier, P Klopp… - Acta …, 2022 - Springer
The gut–brain–beta cell glucagon-like peptide-1 (GLP-1)-dependent axis and the clock
genes both control insulin secretion. Evidence shows that a keystone of this molecular …
genes both control insulin secretion. Evidence shows that a keystone of this molecular …
[CITATION][C] A Specific Gut Microbiota Dysbiosis of Type 2 Diabetic Mice Induces GLP-1 Resistance through an Enteric NO-Dependent and Gut-Brain Axis Mechanism …
E Grasset, A Puel, J Charpentier… - CELL …, 2017 - CELL PRESS 50 HAMPSHIRE ST …