[HTML][HTML] Emerging role of immune checkpoint blockade in pancreatic cancer

S Macherla, S Laks, AR Naqash, A Bulumulle… - International journal of …, 2018 - mdpi.com
Immune checkpoint blockade (ICB) with programmed cell death protein-1 (PD-
1)/programmed death ligand-1 (PD-L1) antibodies has revolutionized the management of …

[HTML][HTML] Treatment-related toxicity and improved outcome from immunotherapy in hepatocellular cancer: evidence from an FDA pooled analysis of landmark clinical …

DJ Pinato, TU Marron, PS Mishra-Kalyani… - European Journal of …, 2021 - Elsevier
Purpose The development of treatment-related adverse events (trAE) correlates favorably
with clinical outcomes in multiple studies of patients receiving immune checkpoint inhibitors …

[HTML][HTML] Immunotherapy in hepatocellular cancer patients with mild to severe liver dysfunction: adjunctive role of the ALBI grade

DJ Pinato, T Kaneko, A Saeed, T Pressiani, A Kaseb… - Cancers, 2020 - mdpi.com
Immune checkpoint inhibitors (ICI) have shown positive results in patients with
hepatocellular carcinoma (HCC). As liver function contributes to prognosis, its precise …

Early antibiotic exposure is not detrimental to therapeutic effect from immunotherapy in hepatocellular carcinoma

P Fessas, M Naeem, M Pinter, TU Marron, D Szafron… - Liver Cancer, 2021 - karger.com
Abstract Background and Rationale: Immune checkpoint inhibitor (ICI) therapy is an
expanding therapeutic option for hepatocellular carcinoma (HCC). Antibiotics (ATB) taken …

[HTML][HTML] Post-registration experience of nivolumab in advanced hepatocellular carcinoma: an international study

P Fessas, A Kaseb, Y Wang, A Saeed… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Original research: Post-registration experience of nivolumab in advanced hepatocellular
carcinoma: an international study - PMC Back to Top Skip to main content NIH NLM Logo …

[HTML][HTML] Impact of corticosteroid therapy on the outcomes of hepatocellular carcinoma treated with immune checkpoint inhibitor therapy

DJ Pinato, A Kaseb, Y Wang, A Saeed… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
The impact of corticosteroid therapy (CT) on efficacy of immune checkpoint inhibitors (ICI) is
undefined in hepatocellular carcinoma (HCC). We evaluated whether CT administered at …

[PDF][PDF] Patterns and outcomes of subsequent therapy after immune checkpoint inhibitor discontinuation in HCC

R Sharma, A Pillai, TU Marron, P Fessas… - Hepatology …, 2022 - Wiley Online Library
The availability of immune checkpoint inhibitors (ICIs) for the management of advanced
hepatocellular cancer (HCC) has changed the treatment paradigm. There are emerging …

Association of Extended Dosing Intervals or Delays in Pembrolizumab-based Regimens With Survival Outcomes in Advanced Non–small-cell Lung Cancer

K Sehgal, A Bulumulle, H Brody, RR Gill, S Macherla… - Clinical lung cancer, 2021 - Elsevier
Background Besides modeling/simulation-based analysis, no post-approval studies have
evaluated the optimal administration frequency of pembrolizumab in non–small-cell lung …

[HTML][HTML] Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature

J Vera-Aguilera, O Mukarram, P Nutalapati… - Journal of Medical Case …, 2016 - Springer
Background Acute myeloid leukemia is typically a disease of the older population and
presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of …

The real-world incidence of immunotherapy-related thyroid dysfunction: A retrospective analysis of a single center's experience over five years.

HM Brody, S Macherla, A Bulumulle, P Namireddy… - 2020 - ascopubs.org
98 Background: Immunotherapy related thyroid abnormalities are well described. Any grade
abnormality has been reported in 6-18% of patients. The clinical relevance of thyroid …