Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine …

Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor …

Cancers often arise as the end stage of inflammation in adults, but not in children. As such
there is a complex interplay between host immune cells during neoplastic development, with …

Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …

A patient with progressive metastatic pancreatic cancer was treated with a single infusion of
16.2× 109 autologous T cells that had been genetically engineered to clonally express two …

Direct gene transfer offers the potential to introduce DNA encoding therapeutic proteins to
treat human disease. Previously, gene transfer in humans has been achieved by a cell …

Identifying tumor antigen-specific T cells from cancer patients has important implications for
immunotherapy diagnostics and therapeutics. Here, we show that CD103+ CD39+ tumor …

The outcome prediction in cancer is usually achieved by evaluating tissue samples obtained
during surgical removal of the primary tumor focusing on their histopathological …

OX40 is a potent costimulatory receptor that can potentiate T-cell receptor signaling on the
surface of T lymphocytes, leading to their activation by a specifically recognized antigen. In …

PURPOSE The purpose of this study was to evaluate the prognostic value of Immunoscore
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …