The genome sequence archive family: toward explosive data growth and diverse data types
T Chen, X Chen, S Zhang, J Zhu, B Tang… - Genomics …, 2021 - academic.oup.com
Abstract The Genome Sequence Archive (GSA) is a data repository for archiving raw
sequence data, which provides data storage and sharing services for worldwide scientific …
sequence data, which provides data storage and sharing services for worldwide scientific …
GSA: genome sequence archive
With the rapid development of sequencing technologies towards higher throughput and
lower cost, sequence data are generated at an unprecedentedly explosive rate. To provide …
lower cost, sequence data are generated at an unprecedentedly explosive rate. To provide …
Safety, efficacy, and biomarker analysis of toripalimab in previously treated advanced melanoma: results of the POLARIS-01 multicenter phase II trial
B Tang, Z Chi, Y Chen, X Liu, D Wu, J Chen… - Clinical Cancer …, 2020 - AACR
Purpose: In contrast to the predominant chronic UV exposure–induced cutaneous
melanoma in Caucasians, acral and mucosal comprise the majority of melanomas in Asia …
melanoma in Caucasians, acral and mucosal comprise the majority of melanomas in Asia …
Phase II randomized trial comparing high-dose IFN-α2b with temozolomide plus cisplatin as systemic adjuvant therapy for resected mucosal melanoma
B Lian, L Si, C Cui, Z Chi, X Sheng, L Mao, S Li… - Clinical Cancer …, 2013 - AACR
Purpose: Mucosal melanoma is rare and associated with extremely poor prognosis.
However, standard adjuvant therapy for mucosal melanoma has not been established. We …
However, standard adjuvant therapy for mucosal melanoma has not been established. We …
Early use of high-dose glucocorticoid for the management of irAE is associated with poorer survival in patients with advanced melanoma treated with anti–PD-1 …
Purpose: Programmed cell death receptor-1 (PD-1) inhibitors are frontline therapy in
advanced melanoma. Severe immune-related adverse effects (irAEs) often require …
advanced melanoma. Severe immune-related adverse effects (irAEs) often require …
[HTML][HTML] Axitinib in combination with toripalimab, a humanized immunoglobulin G4 monoclonal antibody against programmed cell death-1, in patients with metastatic …
X Sheng, X Yan, Z Chi, L Si, C Cui, B Tang… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
PURPOSE Metastatic mucosal melanoma responds poorly to anti–programmed cell death-1
(PD-1) monotherapy. Vascular endothelial growth factor (VEGF) has been shown to play an …
(PD-1) monotherapy. Vascular endothelial growth factor (VEGF) has been shown to play an …
[HTML][HTML] Safety and clinical activity with an anti-PD-1 antibody JS001 in advanced melanoma or urologic cancer patients
B Tang, X Yan, X Sheng, L Si, C Cui, Y Kong… - Journal of hematology & …, 2019 - Springer
Background JS001, a humanized IgG 4 monoclonal antibody against the programmed death-
1 (PD-1) receptor, blocks the interaction of PD-1 with its ligands and promotes T cell …
1 (PD-1) receptor, blocks the interaction of PD-1 with its ligands and promotes T cell …
GWAS Atlas: a curated resource of genome-wide variant-trait associations in plants and animals
D Tian, P Wang, B Tang, X Teng, C Li… - Nucleic Acids …, 2020 - academic.oup.com
Abstract GWAS Atlas (https://bigd. big. ac. cn/gwas/) is a manually curated resource of
genome-wide variant-trait associations for a wide range of species. Unlike existing related …
genome-wide variant-trait associations for a wide range of species. Unlike existing related …
GWAS Atlas: an updated knowledgebase integrating more curated associations in plants and animals
X Liu, D Tian, C Li, B Tang, Z Wang… - Nucleic Acids …, 2023 - academic.oup.com
Abstract GWAS Atlas (https://ngdc. cncb. ac. cn/gwas/) is a manually curated resource of
genome-wide genotype-to-phenotype associations for a wide range of species. Here, we …
genome-wide genotype-to-phenotype associations for a wide range of species. Here, we …
MAPK Pathway and TERT Promoter Gene Mutation Pattern and Its Prognostic Value in Melanoma Patients: A Retrospective Study of 2,793 Cases
X Bai, Y Kong, Z Chi, X Sheng, C Cui, X Wang… - Clinical Cancer …, 2017 - AACR
Purpose: Ethnic differences are conspicuous in melanoma. This study is to obtain a
comprehensive view of a genomic landscape and a better understanding of the correlations …
comprehensive view of a genomic landscape and a better understanding of the correlations …