User profiles for "author:Bryan E Strauss"

Bryan E. Strauss

Coordenador de Pesquisa Medica, Instituto do Cancer do Estado de Sao Paulo
Verified email at usp.br
Cited by 3342

[HTML][HTML] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

L Galluzzi, I Vitale, S Warren, S Adjemian… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …

[HTML][HTML] Immunomodulatory and antitumor effects of type I interferons and their application in cancer therapy

RFV Medrano, A Hunger, SA Mendonça, JAM Barbuto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
During the last decades, the pleiotropic antitumor functions exerted by type I interferons
(IFNs) have become universally acknowledged, especially their role in mediating …

Human multipotent adipose‐derived stem cells restore dystrophin expression of Duchenne skeletal‐muscle cells in vitro

NM Vieira, V Brandalise, E Zucconi, T Jazedje… - Biology of the …, 2008 - Wiley Online Library
Background information. DMD (Duchenne muscular dystrophy) is a devastating X‐linked
disorder characterized by progressive muscle degeneration and weakness. The use of cell …

[HTML][HTML] Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and …

CJ Alves, R Dariolli, FM Jorge, MR Monteiro… - Frontiers in cellular …, 2015 - frontiersin.org
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that leads to
widespread motor neuron death, general palsy and respiratory failure. The most prevalent …

[HTML][HTML] Overhauling CAR T cells to improve efficacy, safety and cost

L Chicaybam, MH Bonamino, A Luckow Invitti… - Cancers, 2020 - mdpi.com
Gene therapy is now surpassing 30 years of clinical experience and in that time a variety of
approaches has been applied for the treatment of a wide range of pathologies. While the …

[HTML][HTML] Mesenchymal bone marrow stem cells within polyglycolic acid tube observed in vivo after six weeks enhance facial nerve regeneration

HJZR Costa, RF Bento, R Salomone, D Azzi-Nogueira… - Brain research, 2013 - Elsevier
Autografting is the gold-standard method for facial nerve repair with tissue loss. Its
association with high-quality scaffolds and cell implants has disclosed distinct experimental …

Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells

LK Lerner, G Francisco, DT Soltys… - Nucleic acids …, 2017 - academic.oup.com
Genome lesions trigger biological responses that help cells manage damaged DNA,
improving cell survival. Pol eta is a translesion synthesis (TLS) polymerase that bypasses …

Production of Lentivirus for the Establishment of CAR-T Cells

MG Lana, BE Strauss - Chimeric Antigen Receptor T Cells: Development …, 2020 - Springer
One of the most versatile gene transfer methods involves the use of recombinant lentiviral
vectors since they can transduce both dividing and nondividing cells, are considered to be …

Combination of cabazitaxel and p53 gene therapy abolishes prostate carcinoma tumor growth

RE Tamura, MG Lana, E Costanzi-Strauss, BE Strauss - Gene therapy, 2020 - nature.com
For patients with metastatic prostate cancer, the 5-year survival rate of 31% points to a need
for novel therapies and improvement of existing modalities. We propose that p53 gene …

Retinoic acid and VEGF delay smooth muscle relative to endothelial differentiation to coordinate inner and outer coronary vessel wall morphogenesis

AP Azambuja, V Portillo-Sanchez… - Circulation …, 2010 - Am Heart Assoc
Rationale: Major coronary vessels derive from the proepicardium, the cellular progenitor of
the epicardium, coronary endothelium, and coronary smooth muscle cells (CoSMCs) …