Once thought to be a part of the 'dark matter'of the genome, long non-coding RNAs
(lncRNAs) are emerging as an integral functional component of the mammalian …

Early identification of high-risk disease could greatly reduce both mortality and morbidity due
to oral cancer. We describe a simple handheld device that facilitates the direct visualization …

A new paradigm in the way we envision tissue change during carcinogenesis has evolved in
recent years. From a clinical standpoint, this paradigm has altered how we view “at-risk” …

DNA methylation is an epigenetic modification that is highly disrupted in response to
cigarette smoke and involved in a wide spectrum of malignant and nonmalignant diseases …

Advances in high-throughput, genome-wide profiling technologies have allowed for an
unprecedented view of the cancer genome landscape. Specifically, high-density microarrays …

Oral epithelial dysplasias are believed to progress through a series of histopathological
stages; from mild to severe dysplasia, to carcinoma in situ, and finally to invasive OSCC …

Objective: Volatile organic compounds (VOCs) in exhaled breath as measured by electronic
nose (e-nose) have utility as biomarkers to detect subjects at risk of having lung cancer in a …

Oral cancer is a substantial, though often unrecognized issue globally, with close to 300,000
new cases reported annually (18). The disease presents a management conundrum. It …

The optical properties (absorption coefficient, scattering coefficient and the anisotropic factor
of scattering) and fluorescence characteristics of normal and abnormal bronchial tissue were …

Importance The prevalence of genetically altered cells in oral cancers has a negative
influence on the locoregional recurrence rate and lowers survival. Fluorescence …