[HTML][HTML] Molecular targeted therapies in metastatic prostate cancer: recent advances and future challenges
C Sorrentino, E Di Carlo - Cancers, 2023 - mdpi.com
Simple Summary Recent studies have highlighted the importance of molecular targeted
therapies in metastatic castration-resistant prostate cancer. These therapies, which aim to …
therapies in metastatic castration-resistant prostate cancer. These therapies, which aim to …
Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy
I Airoldi, E Di Carlo, C Cocco, C Sorrentino, F Fais… - Blood, 2005 - ashpublications.org
The interleukin-12 receptor β2 (Il12rb2) gene is silenced in tumor cells from different human
B-cell malignancies as opposed to their normal counterparts. It was hypothesized that this …
B-cell malignancies as opposed to their normal counterparts. It was hypothesized that this …
Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma
C Cocco, N Giuliani, E Di Carlo, E Ognio, P Storti… - Clinical cancer …, 2010 - AACR
Purpose: Multiple myeloma (MM) derives from plasmablast/plasma cells that accumulate in
the bone marrow. Different microenvironmental factors may promote metastatic …
the bone marrow. Different microenvironmental factors may promote metastatic …
Crucial pathophysiological role of CXCR2 in experimental ulcerative colitis in mice
P Buanne, E Di Carlo, L Caputi… - Journal of Leucocyte …, 2007 - academic.oup.com
Polymorphonuclear leukocyte infiltration and activation into colonic mucosa are believed to
play a pivotal role in mediating tissue damage in human ulcerative colitis (UC). Ligands of …
play a pivotal role in mediating tissue damage in human ulcerative colitis (UC). Ligands of …
[HTML][HTML] Colorectal cancer-associated immune exhaustion involves T and B lymphocytes and conventional NK cells and correlates with a shorter overall survival
C Sorrentino, L D'Antonio, C Fieni, SL Ciummo… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancer worldwide, with a growing
impact on public health and clinical management. Immunotherapy has shown promise in the …
impact on public health and clinical management. Immunotherapy has shown promise in the …
Expression of IL-32 in human lung cancer is related to the histotype and metastatic phenotype
C Sorrentino, E Di Carlo - American journal of respiratory and critical …, 2009 - atsjournals.org
Rationale: A strong link has been recently demonstrated between inflammation and lung
cancer. Thus, we investigated whether the proinflammatory cytokine IL-32 may be involved …
cancer. Thus, we investigated whether the proinflammatory cytokine IL-32 may be involved …
CD25+ regulatory T cell depletion augments immunotherapy of micrometastases by an IL-21-secreting cellular vaccine
A Comes, O Rosso, AM Orengo, E Di Carlo… - The Journal of …, 2006 - journals.aai.org
Abstract IL-21 is an IL-2-like cytokine, signaling through a specific IL-21R and the IL-2R γ-
chain. Because the TS/A mammary adenocarcinoma cells genetically modified to secrete IL …
chain. Because the TS/A mammary adenocarcinoma cells genetically modified to secrete IL …
Androgen deprivation boosts prostatic infiltration of cytotoxic and regulatory T lymphocytes and has no effect on disease-free survival in prostate cancer patients
C Sorrentino, P Musiani, P Pompa, G Cipollone… - Clinical Cancer …, 2011 - AACR
Purpose: The value of neoadjuvant hormone therapy (NHT) prior to radical prostatectomy as
a means of restraining prostate cancer (PCa) and strengthening its immunotherapy is still …
a means of restraining prostate cancer (PCa) and strengthening its immunotherapy is still …
[HTML][HTML] SOX2 boosts major tumor progression genes in prostate cancer and is a functional biomarker of lymph node metastasis
SOX2 boosts major tumor progression genes in prostate cancer and is a functional biomarker
of lymph node metastasis - PMC Back to Top Skip to main content NIH NLM Logo Access keys …
of lymph node metastasis - PMC Back to Top Skip to main content NIH NLM Logo Access keys …
[HTML][HTML] SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation, metastasis-suppressor and pluripotency gene expression
S Esposito, MV Russo, I Airoldi, MG Tupone… - Oncotarget, 2015 - ncbi.nlm.nih.gov
SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation,
metastasis-suppressor and pluripotency gene expression - PMC Back to Top Skip to main …
metastasis-suppressor and pluripotency gene expression - PMC Back to Top Skip to main …