Cetuximab, docetaxel, and cisplatin versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck …

J Guigay, A Aupérin, J Fayette, E Saada-Bouzid… - The Lancet …, 2021 - thelancet.com
Background Results from a phase 2 trial of the TPEx chemotherapy regimen (docetaxel–
platinum–cetuximab) showed promising results, with a median overall survival of 14· 0 …

[HTML][HTML] Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency

JS Heitmann, C Tandler, M Marconato, A Nelde… - Nature …, 2023 - nature.com
T-cell immunity is central for control of COVID-19, particularly in patients incapable of
mounting antibody responses. CoVac-1 is a peptide-based T-cell activator composed of …

[HTML][HTML] Investigation of spleen CXCR4 expression by [68Ga]Pentixafor PET in a cohort of 145 solid cancer patients

R Lewis, S Habringer, M Kircher, M Hefter, CA Peuker… - EJNMMI research, 2021 - Springer
Background The chemokine receptor CXCR4 is frequently overexpressed and associated
with adverse prognosis in most hematopoietic malignancies and solid cancers. Recently …

[HTML][HTML] High-affinity T-cell receptor specific for MyD88 L265P mutation for adoptive T-cell therapy of B-cell malignancies

Ö Çınar, B Brzezicha, C Grunert… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Adoptive transfer of engineered T cells has shown remarkable success in B-cell
malignancies. However, the most common strategy of targeting lineage-specific antigens …

[HTML][HTML] Isolation of neoantigen-specific human T cell receptors from different human and murine repertoires

C Grunert, G Willimsky, CA Peuker, S Rhein… - Cancers, 2022 - mdpi.com
Simple Summary T cell-based immunotherapy has achieved remarkable clinical responses
in patients with cancer. Neoepitope-specific T cells can specifically recognize mutated tumor …

MyD88 L265P Mutation-Specific TCR Gene Therapy for Treatment of B-Cell Lymphoma and Leukemia

Ö Çinar, PM Kloetzel, CA Peuker, U Keller, A Pezzutto… - Blood, 2020 - Elsevier
Adoptive transfer of engineered T cells has shown remarkable success in hematopoietic
malignancies. However, the current most common strategy of targeting lineage-specific …

Future perspective: guidance for young physicians in the German Society of Hematology and Oncology: Network. Participate. Educate

C Oing, CA Peuker, J Müller, M Oldenburg, B Wörmann - Forum, 2018 - Springer
Kaum ein anderes medizinisches Fachgebiet erfährt eine solch rasante Entwicklung wie die
Hämatologie und Medizinische Onkologie. Angesichts der stetig wachsenden Zahl von …

Treatment of metastatic uveal melanoma (mUM) directed by a comprehensive molecular tumour analysis program (CMTA).

S Leyvraz, T Kessler, M Schütte, M Lamping, S Burock… - 2018 - ascopubs.org
9566 Background: There is a lack of active treatment against mUM. Such “hard-to-treat”
tumour might benefit from treatment decisions driven by a complete genomic and …

Therapiemonitoring der neoadjuvanten Radio‑/Chemotherapie

A Holzgreve, M Mäurer, F Gassert, C Oing, S Sulzer… - Die Onkologie, 2023 - Springer
Zusammenfassung Hintergrund Die neoadjuvante Therapie (NAT) dient insbesondere der
Verkleinerung von Tumoren mit Verbesserung der Resektabilität. Bildgebende Verfahren …

Mitgestalter gesucht

F Klein, CA Peuker - Im Fokus Onkologie, 2021 - Springer
Wer nicht nur DGHO-Mitglied wird, sondern auch dem AK Junge DGHO beitritt, eröffnet sich
viele Möglichkeiten zum Mitgestalten, sagt Peuker:„Jedes Mitglied ist eingeladen, an den AK …