User profiles for "author:Chadwan Al Yaghchi"

Chadwan Al Yaghchi

Imperial College Healthcare NHS Trust
Verified email at nhs.net
Cited by 544

Vaccinia virus, a promising new therapeutic agent for pancreatic cancer

CA Yaghchi, Z Zhang, G Alusi, NR Lemoine… - Immunotherapy, 2015 - Future Medicine
The poor prognosis of pancreatic cancer patients signifies a need for radically new
therapeutic strategies. Tumor-targeted oncolytic viruses have emerged as attractive …

Efficiently editing the vaccinia virus genome by using the CRISPR-Cas9 system

M Yuan, W Zhang, J Wang, C Al Yaghchi… - Journal of …, 2015 - Am Soc Microbiol
Vaccinia virus (VACV) continues to be used in immunotherapy for the prevention of
infectious diseases and treatment of cancer since its use for the eradication of smallpox …

A prospective study of voice, swallow, and airway outcomes following tracheostomy for COVID‐19

MJ Rouhani, G Clunie, G Thong, L Lovell… - The …, 2021 - Wiley Online Library
Objective The COVID‐19 pandemic has led to unprecedented demands on healthcare with
many requiring intubation. Tracheostomy insertion has often been delayed and the enduring …

Sarcoidosis of the ear, nose and throat: A review of the literature

N Cereceda‐Monteoliva, MJ Rouhani… - Clinical …, 2021 - Wiley Online Library
Objectives Sarcoidosis is a multisystemic inflammatory disease with extrathoracic
manifestations, most commonly affecting the young and middle‐aged, female and Black …

[HTML][HTML] A new oncolytic Vaccinia virus augments antitumor immune responses to prevent tumor recurrence and metastasis after surgery

J Ahmed, LS Chard, M Yuan, J Wang… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Local recurrence and remote metastasis are major challenges to overcome in
order to improve the survival of patients with cancer after surgery. Oncolytic viruses are a …

Primary immunoglobulin G4-related laryngeal disease: A case series and review of literature

EF Maughan, J Michaels, B Miller… - Clinical Medicine …, 2020 - journals.sagepub.com
Objective: Immunoglobulin G4-related disease (IgG4-RD) is an increasingly recognised
cause of various systemic fibro-inflammatory conditions. However, laryngeal involvement as …

[HTML][HTML] Airway glottic insufficiency

LN Onwordi, C Al Yaghchi - 2019 - europepmc.org
Objectives: Review the pathophysiologic basis of airway glottic insufficiency. Outline the
expected history and physical findings for a patient with airway glottic insufficiency. List the …

Role of planned postchemoradiotherapy selective neck dissection in the multimodality management of head and neck cancer

SAR Nouraei, T Upile, C Al‐Yaghchi, M Lei… - The …, 2008 - Wiley Online Library
Abstract Objective/Hypothesis: To assess the oncologic efficacy and functional outcome of
selective postchemoradiotherapy neck dissection for stage IV head and neck squamous cell …

[PDF][PDF] Cell-intrinsic differences between human airway epithelial cells from children and adults

EF Maughan, RE Hynds, A Pennycuick, E Nigro… - Iscience, 2022 - cell.com
The airway epithelium is a protective barrier that is maintained by the self-renewal and
differentiation of basal stem cells. Increasing age is a principle risk factor for chronic lung …

Percutaneous tracheostomy in patients with COVID-19: sealing the bronchoscope with an in-line suction sheath

C Al Yaghchi, C Ferguson… - British Journal of …, 2020 - bjanaesthesia.org
1. Odor PM, Neun M, Bampoe S, et al. Anaesthesia and COVID-19: infection control. Br J
Anaesth Adv Access 2020. https://doi. org/10.1016/J. BJA. 2020.03. 025. Published April 8 2 …