[HTML][HTML] Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories

C Friedrich, S Schallenberg, M Kirchner… - Nature …, 2021 - nature.com
Formalin-fixed paraffin-embedded (FFPE) tissues are a valuable resource for retrospective
clinical studies. Here, we evaluate the feasibility of (phospho-) proteomics on FFPE lung …

[HTML][HTML] High-affinity T-cell receptor specific for MyD88 L265P mutation for adoptive T-cell therapy of B-cell malignancies

Ö Çınar, B Brzezicha, C Grunert… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Adoptive transfer of engineered T cells has shown remarkable success in B-cell
malignancies. However, the most common strategy of targeting lineage-specific antigens …

In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo

G Willimsky, C Beier, L Immisch, G Papafotiou… - Elife, 2021 - elifesciences.org
Proteasome-catalyzed peptide splicing (PCPS) of cancer-driving antigens could generate
attractive neoepitopes to be targeted by T cell receptor (TCR)-based adoptive T cell therapy …

Neo-splicetopes, new potential targets in tumor T cell therapy? Pros and Caveats

C Beier, A Goede, P Kloetzel - Molecular Immunology, 2022 - Elsevier
Adoptive T cell therapy is by now the most effective immunotherapy, being able to eradicate
large established tumors in selected clinical situations. Through invention of T cell receptor …

Analysis of proteasome-generated antigenic peptides by mass spectrometry

K Textoris-Taube, U Kuckelkorn, C Beier… - … : Methods and Protocols, 2019 - Springer
Mass spectrometry (MS) is today one of the most important analytical techniques in
biosciences. The development of electro spray ionization (ESI) as a gentle method, in which …

[CITATION][C] Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories

C Friedrich, S Schallenberg… - MOLECULAR …, 2022 - ELSEVIER RADARWEG 29, 1043 …