[HTML][HTML] Designing therapeutic cancer vaccines by mimicking viral infections

H Sultan, VI Fesenkova, D Addis, AE Fan… - Cancer Immunology …, 2017 - Springer
The design of efficacious and cost-effective therapeutic vaccines against cancer remains
both a research priority and a challenge. For more than a decade, our laboratory has been …

[HTML][HTML] Poly-IC enhances the effectiveness of cancer immunotherapy by promoting T cell tumor infiltration

H Sultan, J Wu, VI Fesenkova, AE Fan… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Immunotherapies, such as immune checkpoint inhibitors and adoptive cell
therapies, have revolutionized cancer treatment and resulted in complete and durable …

Stability of DNA/anti-DNA complexes. II. Salt lability and avidity.

RL Riley, DJ Addis, RP Taylor - Journal of immunology (Baltimore …, 1980 - journals.aai.org
The kinetics of dissociation of antibody-radiolabeled dsDNA (homogeneous PM2 DNA or
sonicated dsDNA of mw 6 x 10 (5)) complexes at 37 degrees C have been examined via …

Abstract PO011: Systemic administration of Poly-ICLC promotes T cell tumor infiltration generating antitumor responses

H Sultan, J Wu, V Fesenkova, A Fan, D Addis… - Cancer Immunology …, 2021 - AACR
Background: Recent advances in immunotherapy have revolutionized cancer treatment.
Immune checkpoint blockade and adoptive T cell therapy can induce durable responses in …