Immunoreceptors on neutrophils
DJ van Rees, K Szilagyi, TW Kuijpers, HL Matlung… - Seminars in …, 2016 - Elsevier
Neutrophils play a critical role in the host defense against infection, and they are able to
perform a variety of effector mechanisms for this purpose. However, there are also a number …
perform a variety of effector mechanisms for this purpose. However, there are also a number …
[PDF][PDF] Neutrophils kill antibody-opsonized cancer cells by trogoptosis
HL Matlung, L Babes, XW Zhao, M van Houdt… - Cell reports, 2018 - cell.com
Destruction of cancer cells by therapeutic antibodies occurs, at least in part, through
antibody-dependent cellular cytotoxicity (ADCC), and this can be mediated by various Fc …
antibody-dependent cellular cytotoxicity (ADCC), and this can be mediated by various Fc …
[HTML][HTML] G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment
PM Sanz, DJ van Rees, LMJ van Zogchel… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Background Current immunotherapy for patients with high-risk neuroblastoma involves the
therapeutic antibody dinutuximab that targets GD2, a ganglioside expressed on the majority …
therapeutic antibody dinutuximab that targets GD2, a ganglioside expressed on the majority …
Sodium stibogluconate and CD47-SIRPα blockade overcome resistance of anti-CD20–opsonized B cells to neutrophil killing
DJ van Rees, M Brinkhaus, B Klein… - Blood …, 2022 - ashpublications.org
Anti-CD20 antibodies such as rituximab are broadly used to treat B-cell malignancies. These
antibodies can induce various effector functions, including immune cell-mediated antibody …
antibodies can induce various effector functions, including immune cell-mediated antibody …
[HTML][HTML] Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components
RP Gazendam, A van de Geer, JL van Hamme… - …, 2016 - ncbi.nlm.nih.gov
Granulocyte transfusions are used to treat neutropenic patients with life-threatening bacterial
or fungal infections that do not respond to anti-microbial drugs. Donor neutrophils that have …
or fungal infections that do not respond to anti-microbial drugs. Donor neutrophils that have …
Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody‐dependent cellular cytotoxicity towards cancer cells
LW Treffers, XW Zhao, J van der Heijden… - European journal of …, 2018 - Wiley Online Library
The efficacy of cancer therapeutic antibodies varies considerably among patients. Anti‐
cancer antibodies act through different mechanisms, including antibody‐dependent cellular …
cancer antibodies act through different mechanisms, including antibody‐dependent cellular …
[HTML][HTML] Cancer cells resist antibody-mediated destruction by neutrophils through activation of the exocyst complex
DJ van Rees, P Bouti, B Klein… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Neutrophils kill antibody-opsonized tumor cells using trogocytosis, a unique
mechanism of destruction of the target plasma. This previously unknown cytotoxic process of …
mechanism of destruction of the target plasma. This previously unknown cytotoxic process of …
Response to: Correspondence on" G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment" by …
PM Sanz, DJ van Rees, HL Matlung… - … for Immunotherapy of …, 2021 - jitc.bmj.com
Dear Editor, We appreciate the interest of Dr Mora and Dr Chantada 1 in our recently
published work proposing granulocyte colony-stimulating factor (G-CSF) as a suitable …
published work proposing granulocyte colony-stimulating factor (G-CSF) as a suitable …