[HTML][HTML] Mass production of highly active NK cells for cancer immunotherapy in a GMP conform perfusion bioreactor

K Bröker, E Sinelnikov, D Gustavus… - … in bioengineering and …, 2019 - frontiersin.org
NK cells have emerged as promising candidates for cancer immunotherapy, especially due
to their ability to fight circulating tumor cells thereby preventing metastases formation. Hence …

Bortezomib, dexamethasone, and fibroblast growth factor receptor 3–specific tyrosine kinase inhibitor in t (4; 14) myeloma

G Bisping, D Wenning, M Kropff, D Gustavus… - Clinical Cancer …, 2009 - AACR
Purpose: Novel drugs including targeted approaches have changed treatment paradigms for
multiple myeloma (MM) and may also have therapeutic potential in the poor-prognosis t (4; …

Genetic background of different cancer cell lines influences the gene set involved in chromosome 8 mediated breast tumor suppression

S Seitz, E Korsching, J Weimer… - Genes …, 2006 - Wiley Online Library
Several lines of evidence suggest that chromosome 8 is likely to harbor tumor‐suppressor
genes involved in breast cancer. We showed previously that microcell‐mediated transfer of …

[HTML][HTML] Generation of colon cancer–derived tumor-infiltrating T cells (TILs) for adoptive cell therapy

HC Albrecht, D Gustavus, J Schwanemann… - Cytotherapy, 2023 - Elsevier
Adoptive cell therapy (ACT) using specific immune cells and stem cells has emerged as a
promising treatment option that could complement traditional cancer therapies in the future …

[HTML][HTML] Tumor-infiltrating lymphocytes mediate complete and durable remission in a patient with NY-ESO-1 expressing prostate cancer

J Karbach, D Kiselicki, K Brand, C Wahle… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Adoptive transfer of autologous tumor-specific lymphocytes represents a viable treatment
method for patients with advanced malignancies. Here, we report a patient's case with …

Profile of differentially expressed genes after transfer of chromosome 17 into the breast cancer cell line CAL51

C Klebig, S Seitz, E Korsching… - Genes …, 2005 - Wiley Online Library
Previous studies have shown that transfer of chromosome 17 suppresses the tumorigenic
phenotype of the breast cancer cell line CAL51, suggesting the presence of putative tumor …

Anti-myeloma activity of LDC-000067, a novel selective inhibitor of cyclin dependent kinase 9: A targeted approach

K Niepoth, D Gustavus, D Wenning, M Meisterernst… - 2011 - ashpublications.org
Abstract Abstract 5110 Background: Cyclin-dependent kinase (CDK) inhibitors are reported
to induce apoptosis in myeloma cells (Gojo et al., 2002; MacCallum et al., 2005). Here we …

[HTML][HTML] Characterization of Hematopoietic Progenitor Kinase 1 (HPK1) in Multiple Myeloma: a Player in Pathogenesis?

G Bisping, D Gustavus, F Kiefer, E Korsching, J Kienast… - Blood, 2011 - Elsevier
Abstract 3956 Hematopoietic progenitor kinase 1 (HPK1) is a differentially regulated MAP4
kinase (MAP4K) in B lymphocytes (Geisberger et al., 2002; Königsberger et al., 2010). In …

[CITATION][C] Tumor-infiltratinglymphocytesmediate completeanddurableremissionina patientwithNY-ESO-1 expressing prostatecancer

J Karbach, D Kiselicki, K Brand, C Wahle, E Sinelnikov… - europepmc.org
Adoptive transfer of autologous tumor-specific lymphocytes represents a viable treatment
method for patients with advanced malignancies. Here, we report a patient's case with …

[PDF][PDF] Dreidimensionale Visualisierung synaptischer Körperchen im ersten und zweiten Neuron der Sehbahn

H Jastrow, DB Gustavus, G Kolios, L Vollrath - Ann Anat, 2000 - anatomy-images.de
Die glutamatergen Synapsen von Sinneszellen mit hoher Entladungsrate weisen
synaptische Körperchen (SK) auf. In der Retina sind diese an der Signaltransduktion …