User profiles for "author:Doncho V Zhelev"
Doncho V ZhelevUniversity of Pittsburgh Verified email at pitt.edu Cited by 3030 |
Tension-stabilized pores in giant vesicles: determination of pore size and pore line tension
We present the first observations of giant, long-existing, stabilized pores in vesicle
membranes. Using a new experimental technique for studying the electropermeabilization of …
membranes. Using a new experimental technique for studying the electropermeabilization of …
[PDF][PDF] Identification of GPC2 as an oncoprotein and candidate immunotherapeutic target in high-risk neuroblastoma
We developed an RNA-sequencing-based pipeline to discover differentially expressed cell-
surface molecules in neuroblastoma that meet criteria for optimal immunotherapeutic target …
surface molecules in neuroblastoma that meet criteria for optimal immunotherapeutic target …
[PDF][PDF] Role of the membrane cortex in neutrophil deformation in small pipets
The simplest model for a neutrophil in its" passive" state views the cell as consisting of a
liquid-like cytoplasmic region surrounded by a membrane. The cell surface is in a state of …
liquid-like cytoplasmic region surrounded by a membrane. The cell surface is in a state of …
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection
Effective therapies are urgently needed for the SARS-CoV-2/COVID-19 pandemic. We
identified panels of fully human monoclonal antibodies (mAbs) from large phage-displayed …
identified panels of fully human monoclonal antibodies (mAbs) from large phage-displayed …
[HTML][HTML] Material property characteristics for lipid bilayers containing lysolipid
DV Zhelev - Biophysical journal, 1998 - cell.com
The apparent area expansion modulus and tensile strength of egg phosphatidylcholine
(EPC) membranes are measured in the presence of monooleoylphosphatidylcholine …
(EPC) membranes are measured in the presence of monooleoylphosphatidylcholine …
[PDF][PDF] Exchange of monooleoylphosphatidylcholine as monomer and micelle with membranes containing poly (ethylene glycol)-lipid
Surface-grafted polymers, such as poly (ethylene glycol)(PEG), provide an effective steric
barrier against surface-surface and surface-macromolecule interactions. In the present work …
barrier against surface-surface and surface-macromolecule interactions. In the present work …
Function and regulation of chemoattractant receptors
B Haribabu, RM Richardson, MW Verghese… - Immunologic …, 2000 - Springer
Phagocyte migration and activation at sites of inflammation is mediated through
chemoattractant receptors that are coupled to G-proteins. Early studies from our laboratory …
chemoattractant receptors that are coupled to G-proteins. Early studies from our laboratory …
Lysolipid exchange with lipid vesicle membranes
While the aqueous solubility for bilayer phospholipids is less than 10− 10 M—keeping lipid
membranes at essentially constant mass, single chain surfactants can have a significant …
membranes at essentially constant mass, single chain surfactants can have a significant …
[PDF][PDF] Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants
DV Zhelev, AM Alteraifi, D Chodniewicz - Biophysical journal, 2004 - cell.com
The formation of pseudopods and lamellae after ligation of chemoattractant sensitive G-
protein coupled receptors (GPCRs) is essential for chemotaxis. Here, pseudopod extension …
protein coupled receptors (GPCRs) is essential for chemotaxis. Here, pseudopod extension …
[PDF][PDF] A novel micropipet method for measuring the bending modulus of vesicle membranes
A theoretical model and an experiment are presented for determining the bending modulus
of a bilayer vesicle membrane. The vesicle is held with a pipet having a radius between 1 …
of a bilayer vesicle membrane. The vesicle is held with a pipet having a radius between 1 …