[HTML][HTML] Profiling specific cell populations within the inflammatory tumor microenvironment by oscillating-gradient diffusion-weighted MRI

E Hoffmann, M Gerwing, S Niland… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background The inflammatory tumor microenvironment (TME) is formed by various immune
cells, being closely associated with tumorigenesis. Especially, the interaction between tumor …

Spectral diffusion analysis of kidney intravoxel incoherent motion MRI in healthy volunteers and patients with renal pathologies

J Stabinska, A Ljimani, HJ Zöllner… - Magnetic …, 2021 - Wiley Online Library
Purpose To assess the feasibility of measuring tubular and vascular signal fractions in the
human kidney using nonnegative least‐square (NNLS) analysis of intravoxel incoherent …

[HTML][HTML] Resolving immune cells with patrolling behaviour by magnetic resonance time-lapse single cell tracking

M Masthoff, FN Freppon, L Zondler, E Wilken… - …, 2021 - thelancet.com
Background Immune cells show distinct motion patterns that change upon inflammatory
stimuli. Monocytes patrol the vasculature to screen for pathogens, thereby exerting an early …

Dynamic cell tracking using time‐lapse MRI with variable temporal resolution Cartesian sampling

M Armstrong, E Wilken, F Freppon… - Magnetic …, 2023 - Wiley Online Library
Purpose Temporal resolution of time‐lapse MRI to track individual iron‐labeled cells is
limited by the required data‐acquisition time to fill k‐space and to reach sufficient SNR …

Radial compressed sensing imaging improves the velocity detection limit of single cell tracking time‐lapse MRI

E Wilken, A Havlas, M Masthoff… - Magnetic …, 2024 - Wiley Online Library
Purpose Time‐lapse MRI enables tracking of single iron‐labeled cells. Yet, due to temporal
blurring, only slowly moving cells can be resolved. To study faster cells for example during …

Supplementary material: Profiling specific cell populations within the inflammatory tumor microenvironment by oscillating-gradient diffusion-weighted MRI

E Hoffmann, M Gerwing, S Niland, R Niehoff… - jitc.bmj.com
Suppl. Figure 5: Impact of fixed Din on cell radius calculation. Suppl. Figure 6: Impact of
estimated vin and Dex on cell radius calculation. Suppl. Figure 7: Analysis of IMPULSED …

Detectable velocity range in single-cell tracking by time-lapse MRI

E Wilken, F Freppon, M Masthoff, C Faber - archive.ismrm.org
Repetitive T2*-weighted image acquisition in vivo and contrast simulations were used to
show that single iron oxide nanoparticle labeled cells can be resolved and tracked non …

Time-lapse MRI: in vivo single-cell tracking of patrolling immune cells

E Wilken, I Fredrich, A Havlas, F Freppon, M Masthoff… - archive.ismrm.org
We validate that time-lapse MRI is able to resolve and follow single immune cells patrolling
the brain vasculature. For that reason, we simulate motion-dependent contrast based on …

Variable Temporal Resolution Cartesian Sampling for Cell Tracking MRI

M Armstrong, F Freppon, E Wilken, M Masthoff, C Faber… - archive.ismrm.org
Individual iron oxide nanoparticle labelled immune cells can be visualized with a dynamic
MRI image series. Time-lapse MRI can provide insights in the studies of inflammatory …

[CITATION][C] Time-lapse MRI single cell tracking of iron labeled monocytes with velocities of 1 µm/s

E Wilken