Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …

Historically, the nature and extent of host damage by a microbe were considered highly
dependent on virulence attributes of the microbe. However, it has become clear that disease …

Periodontal disease (PD) is one of the most ubiquitous diseases of mankind, considered to
be the second most common dental disease worldwide, after dental decay. This chronic …

Biofilm-associated polymicrobial infections, particularly those involving fungi and bacteria,
are responsible for significant morbidity and mortality and tend to be challenging to treat …

Methicillin-resistant Staphylococcus aureus (MRSA), or multidrug-resistant S. aureus, first
reported in the early 1960s in the United Kingdom, are strains of S. aureus that through the …

Abstract Introduction We assessed the Aurora A kinase inhibitor, alisertib, plus paclitaxel
(henceforth referred to as alisertib/paclitaxel) as second-line treatment for SCLC. Methods In …

Whether in human, animal, or microbial communities, the resolve to coexist is the
quintessence of survival. Therefore, in natural habitats where resources are limited …

Background Immune checkpoint inhibitors (ICIs) have expanded treatment options for
metastatic renal cell carcinoma (mRCC); however, there are limited predictive biomarkers for …

In microbial biofilms, microorganisms utilize secreted signaling chemical molecules to
coordinate their collective behavior. Farnesol is a quorum sensing molecule secreted by the …

The clinical significance of polymicrobial interactions, particularly those between commensal
species with high pathogenic potential, remains largely understudied. Although the …