Aim of the study Patients with cancer might have an increased risk for severe outcome of
coronavirus disease 2019 (COVID-19). To identify risk factors associated with a worse …

Background: Thyroid dysfunction is among the most common adverse effects during anti-
programmed cell death 1 (PD-1) immunotherapy, and alongside correlations with elevated …

Background Addition of deep hyperthermia results in improved local control (LC) and overall
survival (OS) compared to radiotherapy alone in patients with cervical carcinoma …

Importance Death rattle, defined as noisy breathing caused by the presence of mucus in the
respiratory tract, is relatively common among dying patients. Although clinical guidelines …

Background: High-grade glioma cells consume mainly glucose and cannot compensate for
glucose restriction. Apoptosis may potentially occur under carbohydrate restriction by a …

Background A minority of patients with advanced non-small-cell lung cancer (NSCLC)
benefit from treatment with immune checkpoint inhibitors (ICIs). Ineffective effector function of …

Introduction Nivolumab treatment is subject to large interpatient variability in both efficacy
and toxicity, which may partly be explained by differences in nivolumab exposure. Exposure …

Purpose: CPC634 is a novel nanoparticle entrapping docetaxel, developed to enhance the
intratumoral chemotherapy exposure. This randomized cross-over study compared the …

Background Treatment with PD-1 inhibitors can be hampered by severe auto-immune-
related toxicities. Our objective was to identify single-nucleotide polymorphisms (SNPs) in …

Purpose In the multicenter, phase 3, HYpofractionated irradiation for PROstate cancer trial,
hypofractionated (HF) radiation therapy was compared with conventionally fractionated (CF) …