DNA polymerase θ up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability

F Lemée, V Bergoglio… - Proceedings of the …, 2010 - National Acad Sciences
“Replicative stress” is one of the main factors underlying neoplasia from its early stages.
Genes involved in DNA synthesis may therefore represent an underexplored source of …

[HTML][HTML] Circulating CD14high CD16low intermediate blood monocytes as a biomarker of ascites immune status and ovarian cancer progression

M Prat, A Le Naour, K Coulson, F Lemée… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Besides the interest of an early detection of ovarian cancer, there is an urgent
need for new predictive and prognostic biomarkers of tumor development and cancer …

[HTML][HTML] Murlentamab, a low fucosylated anti-müllerian hormone type II receptor (AMHRII) antibody, exhibits anti-tumor activity through tumor-associated macrophage …

M Prat, M Salon, T Allain, O Dubreuil, G Noël… - Cancers, 2021 - mdpi.com
Simple Summary AMHRII, the anti-Müllerian hormone receptor, is selectively expressed in
normal sexual organs in healthy adults but is also re-expressed in ovarian, colorectal and …

Anti-Müllerian hormone type II receptor (AMHRII) found expressed in human non-gynecological solid tumors, suggesting potential broader applications for anti …

JMM Barret, D Meseure, G Bataillon, N Andersson… - Cancer Research, 2018 - AACR
The anti-Müllerian hormone (AMH) belongs to the TGF-β family and plays a key role during
fetal sexual development. It has been shown that AMH inhibits proliferation and induces …