During hemolysis, erythrophagocytes dispose damaged red blood cells. This prevents the
extracellular release of hemoglobin, detoxifies heme, and recycles iron in a linked metabolic …

Abstract HIV-1-and cytomegalovirus (CMV)-specific CD4 T-cell-mediated antiviral immunity
was evaluated by assessing the frequency of interleukin 2 (IL-2)-and interferon γ (IFN-γ) …

Functional and phenotypic characterization of virus-specific CD8 T cells against
cytomegalovirus, Epstein-Barr virus, influenza (flu), and HIV-1 were performed on the basis …

Memory CD4 T cell responses are functionally and phenotypically heterogeneous. In the
present study, memory CD4 T cell responses were analyzed in different models of Ag …

Massive transfusion of blood can lead to clinical complications, including multiorgan
dysfunction and even death. Such severe clinical outcomes have been associated with …

Hemolysis is a ubiquitous pathology defined as premature red blood cell destruction within
the circulation or local tissues. One of the most archetypal functions of macrophages is …

Detoxification and clearance of extracellular hemoglobin (Hb) have been attributed to its
removal by the CD163 scavenger receptor pathway. However, even low-level hydrogen …

The factors responsible for the phenotypic heterogeneity of memory CD4 T cells are unclear.
In the present study, we have identified a third population of memory CD4 T cells …

A growing number of patients with SARS-CoV-2 infections experience long-lasting
symptoms. Even patients who suffered from a mild acute infection show a variety of …

Rationale: Hemolysis occurs not only in conditions such as sickle cell disease and malaria
but also during transfusion of stored blood, extracorporeal circulation, and sepsis. Cell-free …