[HTML][HTML] Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials

FC Bidard, T Fehm, M Ignatiadis, JB Smerage… - Cancer and Metastasis …, 2013 - Springer
In 2004, circulating tumor cells (CTC) enumeration by the CellSearch® technique at
baseline and during treatment was reported to be associated with prognosis in metastatic …

Circulating tumor cells in breast cancer patients treated by neoadjuvant chemotherapy: a meta-analysis

FC Bidard, S Michiels, S Riethdorf… - JNCI: Journal of the …, 2018 - academic.oup.com
Background We conducted a meta-analysis in nonmetastatic breast cancer patients treated
by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell …

Circulating tumor cells: clinical validity and utility

L Cabel, C Proudhon, H Gortais, D Loirat… - International journal of …, 2017 - Springer
Circulating tumor cells (CTCs) are rare tumor cells and have been investigated as
diagnostic, prognostic and predictive biomarkers in many types of cancer. Although CTCs …

Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data

FC Bidard, DJ Peeters, T Fehm, F Nolé… - The lancet …, 2014 - thelancet.com
Background We aimed to assess the clinical validity of circulating tumour cell (CTC)
quantification for prognostication of patients with metastatic breast cancer by undertaking a …

Circulating tumor cell detection predicts early metastatic relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II …

JY Pierga, FC Bidard, C Mathiot, E Brain… - Clinical Cancer …, 2008 - AACR
Purpose: Circulating tumor cells in blood from metastatic breast cancer patients have been
reported as a surrogate marker for tumor response and shorter survival. The aim of this study …

Microfluidic sorting and multimodal typing of cancer cells in self-assembled magnetic arrays

AE Saliba, L Saias, E Psychari… - Proceedings of the …, 2010 - National Acad Sciences
We propose a unique method for cell sorting,“Ephesia,” using columns of biofunctionalized
superparamagnetic beads self-assembled in a microfluidic channel onto an array of …

Switch to fulvestrant and palbociclib versus no switch in advanced breast cancer with rising ESR1 mutation during aromatase inhibitor and palbociclib therapy (PADA …

FC Bidard, AC Hardy-Bessard, F Dalenc… - The Lancet …, 2022 - thelancet.com
Background In advanced oestrogen receptor-positive, HER2-negative breast cancer,
acquired resistance to aromatase inhibitors frequently stems from ESR1-mutated subclones …

Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation

A Mousset, E Lecorgne, I Bourget, P Lopez, K Jenovai… - Cancer Cell, 2023 - cell.com
Metastasis is the major cause of cancer death, and the development of therapy resistance is
common. The tumor microenvironment can confer chemotherapy resistance …

[HTML][HTML] Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all …

R Lebofsky, C Decraene, V Bernard, M Kamal, A Blin… - Molecular …, 2015 - Elsevier
Cell-free tumor DNA (ctDNA) has the potential to enable non-invasive diagnostic tests for
personalized medicine in providing similar molecular information as that derived from …

Detection rate and prognostic value of circulating tumor cells and circulating tumor DNA in metastatic uveal melanoma

FC Bidard, J Madic, P Mariani… - … journal of cancer, 2014 - Wiley Online Library
Circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) have been recently
investigated in several cancer types, but their respective clinical significance remains to be …