User profiles for "author:Francesca Ascenzi"
Francesca Ascenzisapienza Verified email at uniroma1.it Cited by 353 |
[HTML][HTML] SCD1, autophagy and cancer: implications for therapy
Background Autophagy is an intracellular degradation system that removes unnecessary or
dysfunctional components and recycles them for other cellular functions. Over the years, a …
dysfunctional components and recycles them for other cellular functions. Over the years, a …
Effects of IGF‐1 isoforms on muscle growth and sarcopenia
F Ascenzi, L Barberi, G Dobrowolny… - Aging cell, 2019 - Wiley Online Library
The decline in skeletal muscle mass and strength occurring in aging, referred as sarcopenia,
is the result of many factors including an imbalance between protein synthesis and …
is the result of many factors including an imbalance between protein synthesis and …
[HTML][HTML] ALDOC-and ENO2-driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis
C De Vitis, AM Battaglia, M Pallocca… - Journal of Experimental …, 2023 - Springer
Background Metastases are the major cause of cancer-related morbidity and mortality. By
the time cancer cells detach from their primary site to eventually spread to distant sites, they …
the time cancer cells detach from their primary site to eventually spread to distant sites, they …
[HTML][HTML] Sustained systemic levels of IL-6 impinge early muscle growth and induce muscle atrophy and wasting in adulthood
L Pelosi, MG Berardinelli, L Forcina, F Ascenzi… - Cells, 2021 - mdpi.com
IL-6 is a pleiotropic cytokine that can exert different and opposite effects. The muscle-
induced and transient expression of IL-6 can act in an autocrine or paracrine manner …
induced and transient expression of IL-6 can act in an autocrine or paracrine manner …
Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride‐induced liver cirrhosis
M Giusto, L Barberi, F Di Sario, E Rizzuto… - Physiological …, 2017 - Wiley Online Library
Skeletal muscle myopathy is universal in cirrhotic patients, however, little is known about the
main mechanisms involved. The study aims to investigate skeletal muscle morphological …
main mechanisms involved. The study aims to investigate skeletal muscle morphological …
[HTML][HTML] IL-10, IL-13, Eotaxin and IL-10/IL-6 ratio distinguish breast implant-associated anaplastic large-cell lymphoma from all types of benign late seromas
A Di Napoli, D Greco, G Scafetta, F Ascenzi… - Cancer Immunology …, 2021 - Springer
Breast implant-associated anaplastic large-cell lymphoma (BI-ALCL) is an uncommon
peripheral T cell lymphoma usually presenting as a delayed peri-implant effusion. Chronic …
peripheral T cell lymphoma usually presenting as a delayed peri-implant effusion. Chronic …
[HTML][HTML] Deconvolution of malignant pleural effusions immune landscape unravels a novel macrophage signature associated with worse clinical outcome in lung …
S Bruschini, M Pallocca, E Sperandio… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors are still unable to provide clinical benefit to the
large majority of non-small cell lung cancer (NSCLC) patients. A deeper characterization of …
large majority of non-small cell lung cancer (NSCLC) patients. A deeper characterization of …
[HTML][HTML] B4GALT1 as a New Biomarker of Idiopathic Pulmonary Fibrosis
C De Vitis, M D'Ascanio, A Sacconi… - International Journal of …, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a disease characterized by progressive scarring of the
lung that involves the pulmonary interstitium. The disease may rapidly progress, leading to …
lung that involves the pulmonary interstitium. The disease may rapidly progress, leading to …
[HTML][HTML] B4GALT1 is a new candidate to maintain the stemness of lung cancer stem cells
Background: According to the cancer stem cells (CSCs) hypothesis, a population of cancer
cells with stem cell properties is responsible for tumor propagation, drug resistance, and …
cells with stem cell properties is responsible for tumor propagation, drug resistance, and …
Identification of a set of genes potentially responsible for resistance to ferroptosis in lung adenocarcinoma cancer stem cells
Scientific literature supports the evidence that Cancer Stem Cells (CSCs) retain inside low
Reactive Oxygen Species (ROS) levels and are therefore less susceptible to cell death …
Reactive Oxygen Species (ROS) levels and are therefore less susceptible to cell death …