Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine …

Publisher Summary It is known for some time that malignant transformation of human cells
may be associated with the appearance of tumor associated antigens (TAA). Decades of …

Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor …

The cloning of the genes encoding cancer antigens has opened new possibilities for the
treatment of patients with cancer. In this study, immunodominant peptides from the gp100 …

Immunological memory is thought to depend on a stem cell–like, self-renewing population of
lymphocytes capable of differentiating into effector cells in response to antigen re-exposure …

Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …

The gut microbiota influences both local and systemic inflammation. Inflammation
contributes to development, progression, and treatment of cancer, but it remains unclear …

A unique cohort of HIV-1-infected long term nonprogressors (LTNP) with normal CD4+ T cell
counts and< 50 copies/ml of plasma were prospectively recruited for study. HLA typing …

Background Stimulating an immune response against cancer with the use of vaccines
remains a challenge. We hypothesized that combining a melanoma vaccine with interleukin …

BRAF is a serine/threonine protein kinase activating the MAP kinase/ERK-signaling
pathway. About 50% of melanomas harbors activating BRAF mutations (over 90% V600E) …