LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Despite improvements in medical and surgical therapies, infective endocarditis is associated
with poor prognosis and remains a therapeutic challenge. Many factors affect the outcome of …

Infectious endocarditis remains both a diagnostic and a treatment challenge. A positive
outcome depends on a rapid diagnosis, accurate risk stratification, and a thorough follow-up …

The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

Background—The incidence of embolic events (EE) and death is still high in patients with
infective endocarditis (IE), and data about predictors of these 2 major complications are …

Aims To describe a method for measuring trabeculated left ventricular (LV) mass using
cardiac magnetic resonance imaging and to assess its value in the diagnosis of left …

Immune checkpoint inhibitors (ICIs) represent a major advance in the treatment of cancer.
Although clinical trials reported a low incidence of immune-related cardiovascular adverse …

Objectives: This study sought to determine the value of 18F-fluorodeoxyglucose positron
emission tomography/computed tomography (18F-FDG PET/CT) for diagnosing prosthetic …

Background. Blood culture-negative endocarditis (BCNE) may account for up to 31% of all
cases of endocarditis. Methods. We used a prospective, multimodal strategy incorporating …

Importance Limited information is available on the safety of a rechallenge with an immune
checkpoint inhibitor (ICI) after an immune-related adverse event (irAE). Objective To identify …