[HTML][HTML] Adoptive cellular therapy for multiple myeloma using CAR-and TCR-transgenic T cells: Response and resistance

F Füchsl, AM Krackhardt - Cells, 2022 - mdpi.com
Despite the substantial improvement of therapeutic approaches, multiple myeloma (MM)
remains mostly incurable. However, immunotherapeutic and especially T cell-based …

[HTML][HTML] Paving the way to solid tumors: Challenges and strategies for adoptively transferred transgenic T cells in the tumor microenvironment

F Füchsl, AM Krackhardt - Cancers, 2022 - mdpi.com
Simple Summary Adoptive transfer of T cells targeting tumors still remains mainly ineffective
in solid entities. In this review we discuss challenges related to the tumor microenvironment …

[HTML][HTML] Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma

E Bräunlein, G Lupoli, F Füchsl… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Background Neoantigens derived from somatic mutations correlate with therapeutic
responses mediated by treatment with immune checkpoint inhibitors. Neoantigens are …

High-resolution profiling of neoantigen-specific T cell receptor activation signatures links moderate stimulation patterns to resilience and sustained tumor control

F Füchsl, J Untch, V Kavaka, S Jarosch, C Vogelsang… - bioRxiv, 2022 - biorxiv.org
Neoantigen-specific T cell receptors (neoTCRs) promise a safe, highly personalized
therapeutic approach in anti-tumor immunotherapy. Substantial progress has been made …

Spatial and temporal plasticity of neoantigen-specific T-cell responses bases on characteristics associated to antigen and TCR

E Bräunlein, G Lupoli, ET Abualrous… - bioRxiv, 2021 - biorxiv.org
Neoantigens derived from somatic mutations have been demonstrated to correlate with
therapeutic responses mediated by treatment with immune checkpoint inhibitors …

[CITATION][C] Zeugs

F Füchsl - 2017 - philpapers.org
Franziska Füchsl, Zeugs - PhilPapers Sign in | Create an account PhilPapers PhilPeople
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[CITATION][C] rätsel in großer schrift

F Füchsl - 2020 - edition mosaik