HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy

DC Fajgenbaum, F van Rhee… - Blood, The Journal of the …, 2014 - ashpublications.org
Multicentric Castleman's disease (MCD) describes a heterogeneous group of disorders
involving proliferation of morphologically benign lymphocytes due to excessive …

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease

F Van Rhee, P Voorhees, A Dispenzieri… - Blood, The Journal …, 2018 - ashpublications.org
Castleman disease (CD) describes a group of heterogeneous hematologic disorders with
characteristic histopathological features. CD can present with unicentric or multicentric …

Idiopathic multicentric Castleman's disease: a systematic literature review

AY Liu, CS Nabel, BS Finkelman, JR Ruth… - The Lancet …, 2016 - thelancet.com
Summary Background Multicentric Castleman's disease describes a group of poorly
understood lymphoproliferative disorders driven by proinflammatory hypercytokinaemia …

The molecular classification of multiple myeloma

F Zhan, Y Huang, S Colla, JP Stewart, I Hanamura… - Blood, 2006 - ashpublications.org
To better define the molecular basis of multiple myeloma (MM), we performed unsupervised
hierarchic clustering of mRNA expression profiles in CD138-enriched plasma cells from 414 …

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1

JD Shaughnessy Jr, F Zhan, BE Burington, Y Huang… - Blood, 2007 - ashpublications.org
To molecularly define high-risk disease, we performed microarray analysis on tumor cells
from 532 newly diagnosed patients with multiple myeloma (MM) treated on 2 separate …

[HTML][HTML] Thalidomide and hematopoietic-cell transplantation for multiple myeloma

B Barlogie, G Tricot, E Anaissie… - … England Journal of …, 2006 - Mass Medical Soc
Background High-dose therapy with melphalan can prolong survival among patients with
multiple myeloma. We assessed whether the addition of thalidomide, which has activity …

Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells

F Zhan, J Hardin, B Kordsmeier… - Blood, The Journal …, 2002 - ashpublications.org
Bone marrow plasma cells (PCs) from 74 patients with newly diagnosed multiple myeloma
(MM), 5 with monoclonal gammopathy of undetermined significance (MGUS), and 31 …

CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma

ED Hsi, R Steinle, B Balasa, S Szmania… - Clinical Cancer …, 2008 - AACR
Purpose: We generated a humanized antibody, HuLuc63, which specifically targets CS1
(CCND3 subset 1, CRACC, and SLAMF7), a cell surface glycoprotein not previously …

Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed …

I Hanamura, JP Stewart, Y Huang, F Zhan, M Santra… - Blood, 2006 - ashpublications.org
Using fluorescence in situ hybridization we investigated amplification of chromosome band
1q21 (Amp1q21) in more than 500 untreated patients with monoclonal gammopathy of …

F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma

TB Bartel, J Haessler, TLY Brown… - Blood, The Journal …, 2009 - ashpublications.org
F18-fluorodeoxyglucose positron emission tomography (FDG-PET) is a powerful tool to
investigate the role of tumor metabolic activity and its suppression by therapy for cancer …