User profiles for "author:Greg Jones"

Greg Jones

- Verified email at otago.ac.nz - Cited by 14106

Greg Jones

- Verified email at inivata.com - Cited by 907

Executive onboarding: ensuring the success of the newly hired department chair

WE Ross, KHC Huang, GH Jones - Academic Medicine, 2014 - journals.lww.com
The success of newly recruited medical school department chairs has become increasingly
important for achievement of organizational goals. An effective onboarding program for …

Magnetoencephalographic patterns of epileptiform activity in children with regressive autism spectrum disorders

JD Lewine, R Andrews, M Chez, AA Patil… - …, 1999 - publications.aap.org
Background. One-third of children diagnosed with autism spectrum disorders (ASDs) are
reported to have had normal early development followed by an autistic regression between …

The opioid epidemic in the United States—overview, origins, and potential solutions

GH Jones, E Bruera, S Abdi… - … & Gynecological Survey, 2019 - journals.lww.com
Over the last 20 years, there has been a staggering increase in addiction to opiates and the
number of deaths from opioids in the United States. The initial trigger for the epidemic was a …

The positive impacts of real-world data on the challenges facing the evolution of biopharma

J Wise, A Möller, D Christie, D Kalra, E Brodsky… - Drug discovery today, 2018 - Elsevier
Highlights•Some current challenges facing the biopharmaceutical industry are outlined.•The
importance of Real World Data and Real World Evidence is identified.•Pre-competitive …

[HTML][HTML] Virtual histology of transgenic mouse embryos for high-throughput phenotyping

JT Johnson, MS Hansen, I Wu, LJ Healy… - PLoS …, 2006 - journals.plos.org
A bold new effort to disrupt every gene in the mouse genome necessitates systematic,
interdisciplinary approaches to analyzing patterning defects in the mouse embryo. We …

Arthroscopy-assisted anterior cruciate ligament reconstruction using patellar tendon substitution: two-to four-year follow-up results

BR Bach JR, GT Jones, FA Sweet… - The American Journal …, 1994 - journals.sagepub.com
The purpose of this retrospective study was to evaluate clinically, functionally, and
objectively our initial expe rience using free, autogenous middle third patellar ten don for …

[HTML][HTML] Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC)

B Ricciuti, G Jones, M Severgnini… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Currently available biomarkers are imperfect in their ability to predict responses
to the multiple first-line treatment options available for patients with advanced non-small cell …

[HTML][HTML] Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA

D Gale, ARJ Lawson, K Howarth, M Madi, B Durham… - PloS one, 2018 - journals.plos.org
Introduction Detection and monitoring of circulating tumor DNA (ctDNA) is rapidly becoming
a diagnostic, prognostic and predictive tool in cancer patient care. A growing number of …

MGMT Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical …

ME Hegi, E Genbrugge, T Gorlia, R Stupp… - Clinical Cancer …, 2019 - AACR
Purpose: The methylation status of the O6-methylguanine DNA methyltransferase (MGMT)
gene promoter is predictive for benefit from temozolomide in glioblastoma (GBM). A clinically …

[HTML][HTML] Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling

V Plagnol, S Woodhouse, K Howarth, S Lensing… - PloS one, 2018 - journals.plos.org
Circulating tumor DNA (ctDNA) analysis is being incorporated into cancer care; notably in
profiling patients to guide treatment decisions. Responses to targeted therapies have been …