Prevalence and risk factors of non-alcoholic fatty liver disease in potential living liver donors in Korea: a review of 589 consecutive liver biopsies in a single center
BACKGROUND/AIMS: The aim of the study was to evaluate the prevalence and risk factors
of biopsy-proven non-alcoholic fatty liver disease (NAFLD) in potential living liver donors …
of biopsy-proven non-alcoholic fatty liver disease (NAFLD) in potential living liver donors …
[HTML][HTML] The toxicity of nanoparticles depends on multiple molecular and physicochemical mechanisms
YW Huang, M Cambre, HJ Lee - International journal of molecular …, 2017 - mdpi.com
Nanotechnology is an emerging discipline that studies matters at the nanoscale level.
Eventually, the goal is to manipulate matters at the atomic level to serve mankind. One …
Eventually, the goal is to manipulate matters at the atomic level to serve mankind. One …
Androgen receptor: an overview
C Chang, A Saltzman, S Yeh, W Young… - Critical Reviews™ in …, 1995 - dl.begellhouse.com
The action of androgens in regulating development and growth is mediated by androgen
receptor (AR). AR is a member of the steroid hormone receptor superfamily, a class of …
receptor (AR). AR is a member of the steroid hormone receptor superfamily, a class of …
[HTML][HTML] Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
To examine the role of telomerase in normal and neoplastic growth, the telomerase RNA
component (mTR) was deleted from the mouse germline. mTR−/− mice lacked detectable …
component (mTR) was deleted from the mouse germline. mTR−/− mice lacked detectable …
[HTML][HTML] Role of the INK4a locus in tumor suppression and cell mortality
The cell cycle inhibitor p16 INK4a is inactivated in many human tumors and in families with
hereditary melanoma and pancreatic cancer. Tumor-associated alterations in the INK4a …
hereditary melanoma and pancreatic cancer. Tumor-associated alterations in the INK4a …
[HTML][HTML] The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
J Pomerantz, N Schreiber-Agus, NJ Liégeois… - Cell, 1998 - cell.com
The INK4a gene encodes two distinct growth inhibitors—the cyclin-dependent kinase
inhibitor p16 Ink4a, which is a component of the Rb pathway, and the tumor suppressor p19 …
inhibitor p16 Ink4a, which is a component of the Rb pathway, and the tumor suppressor p19 …
Adjuvant sorafenib for hepatocellular carcinoma after resection or ablation (STORM): a phase 3, randomised, double-blind, placebo-controlled trial
J Bruix, T Takayama, V Mazzaferro, GY Chau… - The lancet …, 2015 - thelancet.com
Background There is no standard of care for adjuvant therapy for patients with
hepatocellular carcinoma. This trial was designed to assess the efficacy and safety of …
hepatocellular carcinoma. This trial was designed to assess the efficacy and safety of …
[HTML][HTML] Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
Single-cell transcriptome profiling of tumour tissue isolates allows the characterization of
heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we …
heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we …
Differential antigen processing by dendritic cell subsets in vivo
D Dudziak, AO Kamphorst, GF Heidkamp, VR Buchholz… - Science, 2007 - science.org
Dendritic cells (DCs) process and present self and foreign antigens to induce tolerance or
immunity. In vitro models suggest that induction of immunity is controlled by regulating the …
immunity. In vitro models suggest that induction of immunity is controlled by regulating the …
[HTML][HTML] Longevity, stress response, and cancer in aging telomerase-deficient mice
Telomere maintenance is thought to play a role in signaling cellular senescence; however, a
link with organismal aging processes has not been established. The telomerase null mouse …
link with organismal aging processes has not been established. The telomerase null mouse …