Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

Importance Standard first-line therapy for advanced or metastatic esophageal carcinoma is
chemotherapy, but the prognosis remains poor. Camrelizumab (an anti–programmed death …

An effective blood-based method for the diagnosis and prognosis of hepatocellular
carcinoma (HCC) has not yet been developed. Circulating tumour DNA (ctDNA) carrying …

The ability to identify a specific cancer using minimally invasive biopsy holds great promise
for improving the diagnosis, treatment selection, and prediction of prognosis in cancer …

Background Upper gastrointestinal cancers (including oesophageal cancer and gastric
cancer) are the most common cancers worldwide. Artificial intelligence platforms using deep …

Circulating tumor DNA (ctDNA) has emerged as a useful diagnostic and prognostic
biomarker in many cancers. Here, we conducted a study to investigate the potential use of …

Background Durable efficacy of immune checkpoint blockade (ICB) occurred in a small
number of patients with metastatic gastric cancer (mGC) and the determinant biomarker of …

Ethnopharmacological relevance Processed from natural minerals, arsenic trioxide (ATO) as
an ancient Chinese medicine has been used to treat diseases for over 2000 years. And it …

Loss of tumor suppressor adenomatous polyposis coli (APC) activates β-catenin to initiate
colorectal tumorigenesis. However, β-catenin (CTNNB1) activating mutations rarely occur in …

Chemo-photothermal therapy shows great potential for inhibiting tumor growth. However,
achieving maximal chemo-photothermal synergistic efficacy is challenging because of the …