Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer …
RK Kelley, M Ueno, C Yoo, RS Finn, J Furuse, Z Ren… - The Lancet, 2023 - thelancet.com
Background Biliary tract cancers, which arise from the intrahepatic or extrahepatic bile ducts
and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide …
and the gallbladder, generally have a poor prognosis and are rising in incidence worldwide …
Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global …
Background Nanoliposomal irinotecan showed activity in a phase 2 study in patients with
metastatic pancreatic ductal adenocarcinoma previously treated with gemcitabine-based …
metastatic pancreatic ductal adenocarcinoma previously treated with gemcitabine-based …
Gemcitabine and oxaliplatin with or without erlotinib in advanced biliary-tract cancer: a multicentre, open-label, randomised, phase 3 study
Background Combination chemotherapy with gemcitabine and a platinum-based agent is
regarded as a standard treatment for patients with advanced biliary-tract cancer. Results of …
regarded as a standard treatment for patients with advanced biliary-tract cancer. Results of …
[HTML][HTML] Perspectives and advances in probiotics and the gut microbiome in companion animals
As the number of households that raise dogs and cats is increasing, there is growing interest
in animal health. The gut plays an important role in animal health. In particular, the …
in animal health. The gut plays an important role in animal health. In particular, the …
High thermal and chemical stability in pyrazolate-bridged metal–organic frameworks with exposed metal sites
Reactions between the tritopic pyrazole-based ligand 1, 3, 5-tris (1H-pyrazol-4-yl) benzene
(H3BTP) and transition metal acetate salts in DMF afford microporous pyrazolate-bridged …
(H3BTP) and transition metal acetate salts in DMF afford microporous pyrazolate-bridged …
Broadly Hysteretic H2 Adsorption in the Microporous Metal−Organic Framework Co(1,4-benzenedipyrazolate)
Reaction of Co (CF3SO3) 2 with the new molecule 1, 4-benzenedi (4′-pyrazolyl)(H2BDP)
in N, N′-diethylformamide (DEF) at 130° C generates the metal− organic framework Co …
in N, N′-diethylformamide (DEF) at 130° C generates the metal− organic framework Co …
Dynamic and redox active pillared bilayer open framework: single-crystal-to-single-crystal transformations upon guest removal, guest exchange, and framework …
A metal-organic pillared bilayer open framework having 3D channels,[Ni2 (C26H52N10)] 3
[BTC] 4⊙ 6C5H5N⊙ 36H2O (BOF-1, 1), has been assembled from bismacrocyclic nickel (II) …
[BTC] 4⊙ 6C5H5N⊙ 36H2O (BOF-1, 1), has been assembled from bismacrocyclic nickel (II) …
Hyperprogressive disease during PD-1 blockade in patients with advanced hepatocellular carcinoma
Background & Aims Programmed cell death-1 (PD-1) inhibitor treatment can cause
hyperprogressive disease (HPD), but the incidence, outcome, and predictive factors of HPD …
hyperprogressive disease (HPD), but the incidence, outcome, and predictive factors of HPD …
Multistep N2 Breathing in the Metal−Organic Framework Co(1,4-benzenedipyrazolate)
A variety of spectroscopic techniques combined with in situ pressure-controlled X-ray
diffraction and molecular simulations have been utilized to characterize the five-step phase …
diffraction and molecular simulations have been utilized to characterize the five-step phase …
A Metal− Organic Bilayer Open Framework with a Dynamic Component: Single-Crystal-to-Single-Crystal Transformations
A metal− organic bilayered open framework,[Ni2 (C26H52N10)] 3 [BTC] 4⊙ 6C5H5N⊙
36H2O (BOF-1, 1), has been prepared by the self-assembly of a new bismacrocyclic nickel …
36H2O (BOF-1, 1), has been prepared by the self-assembly of a new bismacrocyclic nickel …