Bipolar disorder (BPD), probably the most prevalent psychotic disorder in adults, has been
relatively neglected or controversial in children and adolescents over the past century. We …

The bone is a complex organ that is dependent on a tight regulation between bone
formation by osteoblasts (OBs) and bone resorption by osteoclasts (OCs). These processes …

In August 1939, at the 3rd International Neurological Congress in Copenhagen, Professor
Lucio Bini reported on the first use of electricity to induce a seizure for therapeutic purposes …

Background To determine safety and efficacy of single cycle induction treatment with
cisplatin/docetaxel and durvalumab/tremelimumab in stage III-IVB head and neck cancer …

The amount of unfolded proteins is increased in cancer cells, leading to endoplasmic
reticulum (ER) stress. Therefore, cancer cells are sensitive to drugs capable of further …

Background The predictive power of novel biological markers for treatment response to
immune checkpoint inhibitors (ICI) is still not satisfactory for the majority of patients with …

Purpose The first aim of the trial is to study feasibility of combined programmed death protein
ligand 1/cytotoxic T-lymphocyte-associated protein 4 inhibition concomitant to radiotherapy …

In this chapter I discuss the use of yogic techniques for health and prevention and in
medicine and psychiatry in the context of a review of relevant research studies. A synopsis of …

Human space exploration needs stable life support systems for the supply of oxygen, water
and food for each human explorer due to long term missions. The most promising approach …

Euglena gracilis (E. gracilis) is an attractive organism due to its evolutionary history and
substantial potential to produce biochemicals of commercial importance. This study …