User profiles for "author:Ines Malenica"

Ines Malenica

Hepatobiliary Immunopathology Laboratory, Humanitas Research Hospital
Verified email at humanitasresearch.it
Cited by 495

[HTML][HTML] Resident memory T cells, critical components in tumor immunology

F Mami-Chouaib, C Blanc, S Corgnac, S Hans… - … for immunotherapy of …, 2018 - Springer
CD8+ T lymphocytes are the major anti-tumor effector cells. Most cancer immunotherapeutic
approaches seek to amplify cytotoxic T lymphocytes (CTL) specific to malignant cells. A …

[HTML][HTML] Molecular and immunological characterization of biliary tract cancers: a paradigm shift towards a personalized medicine

I Malenica, M Donadon, A Lleo - Cancers, 2020 - mdpi.com
Biliary tract cancers (BTCs) are a group of rare cancers that account for up to 3–5% of
cancer patients worldwide. BTCs include cholangiocarcinoma (CCA), gallbladder cancer …

[HTML][HTML] Recent advances in lung cancer immunotherapy: input of T-cell epitopes associated with impaired peptide processing

M Leclerc, L Mezquita, G Guillebot De Nerville… - Frontiers in …, 2019 - frontiersin.org
Recent advances in lung cancer treatment are emerging from new immunotherapies that
target T-cell inhibitory receptors, such as programmed cell death-1 (PD-1). However …

[PDF][PDF] CD103+ CD8+ TRM cells accumulate in tumors of anti-PD-1-responder lung cancer patients and are tumor-reactive lymphocytes enriched with Tc17

S Corgnac, I Malenica, L Mezquita, E Auclin… - Cell Reports …, 2020 - cell.com
Summary Accumulation of CD103+ CD8+ resident memory T (T RM) cells in human lung
tumors has been associated with a favorable prognosis. However, the contribution of T RM …

Multimodal single-cell profiling of intrahepatic cholangiocarcinoma defines hyperactivated Tregs as a potential therapeutic target

G Alvisi, A Termanini, C Soldani, F Portale… - Journal of …, 2022 - Elsevier
Background & Aims The landscape and function of the immune infiltrate of intrahepatic
cholangiocarcinoma (iCCA), a rare, yet aggressive tumor of the biliary tract, remains poorly …

[HTML][HTML] Integrin-αV-mediated activation of TGF-β regulates anti-tumour CD8 T cell immunity and response to PD-1 blockade

I Malenica, J Adam, S Corgnac, L Mezquita… - Nature …, 2021 - nature.com
TGF-β is secreted in the tumour microenvironment in a latent, inactive form bound to latency
associated protein and activated by the integrin αV subunit. The activation of latent TGF-β by …

[HTML][HTML] Vaccine therapy in non-small cell lung cancer

M García-Pardo, T Gorria, I Malenica, S Corgnac… - Vaccines, 2022 - mdpi.com
Immunotherapy using immune checkpoint modulators has revolutionized the oncology field,
emerging as a new standard of care for multiple indications, including non-small cell lung …

Electrochemical studies of ropinirole, an anti-Parkinson's disease drug

B Nigović, S Jurić, A Mornar, I Malenica - Journal of Chemical Sciences, 2013 - Springer
Abstract Graphical Abstract The electrochemical behaviour of ropinirole has been examined
for the first time. The voltammetric response attributed to the oxidation of indol-2-one ring …

Role of Tissue-Resident Memory T (TRM) Cells in CD8+ T Cell Immunity and Response to Anti-PD-1 Immunotherapy: Involvement of TGF-β and αV Integrins

I Malenica - 2019 - theses.fr
Résumé La survie des patients atteints de cancer et traités avec des thérapies
conventionnelles reste faible dans plusieurs types de tumeurs. Récemment, une nouvelle …

Electrochemical Behaviour of a Potent Anti-Parkinson's Disease Drug Ropinirole

I Malenica, B Nigović - IX. SUSRET MLADIH KEMIJSKIH INŽENJERA …, 2012 - croris.hr
Sažetak Electroanalytical methods, in particular voltammetric techniques, are well
established in pharmaceutical and biomedical analysis. Cyclic voltammetry is very suitable …