Incidence, mitigation, and management of neurologic adverse events in patients with multiple myeloma (MM) treated with ciltacabtagene autoleucel (cilta-cel) in …

H Einsele, SS Parekh, D Madduri, B Santomasso… - 2021 - ascopubs.org
8028 Background: Cilta-cel (JNJ-68284528) is a chimeric antigen receptor T (CAR-T)-cell
therapy with 2 BCMA-targeting, single-domain antibodies designed to confer high avidity …

THER-09. ONCOLYTIC ADENOVIRUS, DNX-2401, FOR NAIVE DIFFUSE INTRINSIC PONTINE GLIOMAS: A PHASE I CLINICAL TRIAL

I Iñigo-Marco, M Gonzalez-Huarriz… - Neuro …, 2020 - academic.oup.com
BACKGROUND Abnormal p53 function commonly defines high-risk CNS tumors, but
functional restoration has eluded investigators. SGT-53 is a targeted nanomedicine …

IMMU-21. THE COMBINATION OF DELTA-24-ACT WITH AN IMMUNE CHECKPOINT INHIBITOR RESULTS IN ANTI-GLIOMA EFFECT AND IMMUNE MEMORY

M Puigdelloses, V Laspidea, M Garcia-Moure… - Neuro …, 2020 - ncbi.nlm.nih.gov
Oncolytic viruses have become promising therapeutic candidates to treat gliomas. Our group
has developed Delta-24-ACT, an oncolytic adenovirus armed with the positive costimulatory …

CTIM-25. ONCOLYTIC VIRUS FOR DIPG: THE CLINICAL EXPERIENCE WITH DNX-2401

MM Alonso, I Iñigo-Marco, M Garcia-Moure… - Neuro …, 2020 - ncbi.nlm.nih.gov
Despite our increased understanding of Diffuse Intrinsic Pontine Glioma (DIPG) the outcome
remains dismal. Recently we showed that the virus Delta-24-RGD (DNX-2401 in the clinic) …

THER-01. AWAKING THE IMMUNE SYSTEM WITH AN IMMUNO-ONCOLYTIC VIRUS AS A THERAPEUTIC STRATEGY FOR DIPGs

V Laspidea, M Puigdelloses, I Ausejo-Mauleon… - Neuro …, 2020 - ncbi.nlm.nih.gov
Diffuse intrinsic pontine glioma (DIPG) is an aggressive brain tumour, being the leading
cause of paediatric death caused by cancer. Despite all the advances made regarding …

Estudio del grosor íntima-media carotídeo y los niveles séricos de adipocitocinas y cardiotrofina-1 en pacientes con síndrome metabólico

J Gállego Pérez de Larraya - 2013 - portalcientifico.sergas.es
El síndrome metabólico (SM) se caracteriza por la convergencia de varios factores de riesgo
vascular: obesidad abdominal, hipertensión arterial, alteración de la glucemia …

[CITATION][C] PROPHYLAXIS OF LYMPHOMATOUS MENINGITIS WITH DEPOCYTE (R). EXPERIENCIA DE UN CENTRO

S Villar Fernandez… - …, 2016 - FERRATA STORTI FOUNDATION …