[HTML][HTML] Biomarkers of immunotherapy in urothelial and renal cell carcinoma: PD-L1, tumor mutational burden, and beyond
J Zhu, AJ Armstrong, TW Friedlander, W Kim… - … for immunotherapy of …, 2018 - Springer
Immune checkpoint inhibitors targeting the PD-1 pathway have greatly changed clinical
management of metastatic urothelial carcinoma and metastatic renal cell carcinoma …
management of metastatic urothelial carcinoma and metastatic renal cell carcinoma …
Applications of targeted gene capture and next-generation sequencing technologies in studies of human deafness and other genetic disabilities
The goal of sequencing the entire human genome for $1000 is almost in sight. However, the
total costs including DNA sequencing, data management, and analysis to yield a clear data …
total costs including DNA sequencing, data management, and analysis to yield a clear data …
Deep learning in asset pricing
We use deep neural networks to estimate an asset pricing model for individual stock returns
that takes advantage of the vast amount of conditioning information, keeps a fully flexible …
that takes advantage of the vast amount of conditioning information, keeps a fully flexible …
A wireless and battery-less implant for multimodal closed-loop neuromodulation in small animals
Fully implantable wireless systems for the recording and modulation of neural circuits that do
not require physical tethers or batteries allow for studies that demand the use of …
not require physical tethers or batteries allow for studies that demand the use of …
[HTML][HTML] Advanced thermal sensing techniques for characterizing the physical properties of skin
Measurements of the thermal properties of the skin can serve as the basis for a noninvasive,
quantitative characterization of dermatological health and physiological status. Applications …
quantitative characterization of dermatological health and physiological status. Applications …
Unlocking P (V): Reagents for chiral phosphorothioate synthesis
KW Knouse, JN deGruyter, MA Schmidt, B Zheng… - Science, 2018 - science.org
Phosphorothioate nucleotides have emerged as powerful pharmacological substitutes of
their native phosphodiester analogs with important translational applications in antisense …
their native phosphodiester analogs with important translational applications in antisense …
Forest through the trees: Building cross-sections of stock returns
We build cross-sections of asset returns for a given set of characteristics, that is, managed
portfolios serving as test assets, as well as building blocks for tradable risk factors. We use …
portfolios serving as test assets, as well as building blocks for tradable risk factors. We use …
Temporal trends in the treatment of early-and advanced-stage laryngeal cancer in the United States, 1985-2007
Objective To describe trends and 4-year survival rate of surgical and nonsurgical treatment
for laryngeal cancer. Design Observational cross-sectional study. Patients A total of 131 694 …
for laryngeal cancer. Design Observational cross-sectional study. Patients A total of 131 694 …
3D Graphene Network with Covalently Grafted Aniline Tetramer for Ultralong‐Life Supercapacitors
The conducting polymer polyaniline (PANI) has been considered to be a promising
pseudocapacitive electrode material for supercapacitors due to its high specific capacitance …
pseudocapacitive electrode material for supercapacitors due to its high specific capacitance …
[HTML][HTML] LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across multiple cancer types
LC Brown, MD Tucker, R Sedhom… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B) is a
putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may …
putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may …