[PDF][PDF] Liver regeneration

N Fausto, JS Campbell, KJ Riehle - Hepatology, 2006 - Wiley Online Library
During liver regeneration after partial hepatectomy, normally quiescent hepatocytes undergo
one or two rounds of replication to restore the liver mass by a process of compensatory …

[HTML][HTML] The role of hepatocytes and oval cells in liver regeneration and repopulation

N Fausto, JS Campbell - Mechanisms of development, 2003 - Elsevier
The liver has the unique capacity to regulate its growth and mass. In rodents and humans, it
grows rapidly after resection of more than 50% of its mass. This growth process, as well as …

New concepts in liver regeneration

KJ Riehle, YY Dan, JS Campbell… - … of gastroenterology and …, 2011 - Wiley Online Library
The unique ability of the liver to regenerate itself has fascinated biologists for years and has
made it the prototype for mammalian organ regeneration. Harnessing this process has great …

Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma

JS Campbell, SD Hughes… - Proceedings of the …, 2005 - National Acad Sciences
Members of the platelet-derived growth factor (PDGF) ligand family are known to play
important roles in wound healing and fibrotic disease. We show that both transient and …

Rapid membrane effects of steroids in neuroblastoma cells: effects of estrogen on mitogen activated protein kinase signalling cascade and c-fos immediate early gene …

JJ Watters, JS Campbell, MJ Cunningham… - …, 1997 - academic.oup.com
Rapid effects of steroid hormones have been observed in neuronal cells for many years. We
show here, that in the human neuroblastoma cell line SK-N-SH, the membrane impermeable …

Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages

YY Dan, KJ Riehle, C Lazaro, N Teoh… - Proceedings of the …, 2006 - National Acad Sciences
Little is known about the differentiation capabilities of nonhematopoietic cells of the human
fetal liver. We report the isolation and characterization of a human fetal liver multipotent …

Liver regeneration

N Fausto, JS Campbell, KJ Riehle - Journal of hepatology, 2012 - journal-of-hepatology.eu
In this 'Snapshot'article, we take a fresh look at the fundamentals of liver regeneration in light
of recent technical innovations. While the mammalian response to partial hepatectomy (PH) …

Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3

KJ Riehle, JS Campbell, RS McMahan… - The Journal of …, 2008 - rupress.org
Suppressor of cytokine signaling 3 (SOCS3) down-regulates several signaling pathways in
multiple cell types, and previous data suggest that SOCS3 may shut off cytokine activation at …

[HTML][HTML] Heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration

C Mitchell, M Nivison, LF Jackson, R Fox… - Journal of Biological …, 2005 - ASBMB
The mechanisms that regulate the transition between the initial priming phase and DNA
replication in liver regeneration are poorly understood. To study this transition, we compared …

Establishment, characterization, and long-term maintenance of cultures of human fetal hepatocytes

CA Lázaro, EJ Croager, C Mitchell, JS Campbell, C Yu… - Hepatology, 2003 - Elsevier
Cultured human hepatocytes have broad research and clinical applications; however, the
difficulties in culturing rodent and human hepatocytes are well known. These problems …