User profiles for "author:Jessica Roelands"
Jessica RoelandsLeiden University Medical Center Verified email at lumc.nl Cited by 1164 |
[HTML][HTML] NY-ESO-1 based immunotherapy of cancer: current perspectives
R Thomas, G Al-Khadairi, J Roelands… - Frontiers in …, 2018 - frontiersin.org
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-
testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit …
testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit …
[HTML][HTML] Immunogenomic classification of colorectal cancer and therapeutic implications
The immune system has a substantial effect on colorectal cancer (CRC) progression.
Additionally, the response to immunotherapeutics and conventional treatment options (eg …
Additionally, the response to immunotherapeutics and conventional treatment options (eg …
[HTML][HTML] HLA-G: a new immune checkpoint in cancer?
D Krijgsman, J Roelands, W Hendrickx… - International journal of …, 2020 - mdpi.com
Human leukocyte antigen G (HLA-G), known as a central protein in providing immune
tolerance to the fetus in pregnant women, is also studied for a possible role in tumor …
tolerance to the fetus in pregnant women, is also studied for a possible role in tumor …
[PDF][PDF] Germline genetic contribution to the immune landscape of cancer
Understanding the contribution of the host's genetic background to cancer immunity may
lead to improved stratification for immunotherapy and to the identification of novel …
lead to improved stratification for immunotherapy and to the identification of novel …
[HTML][HTML] Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune response
Background An immune active cancer phenotype typified by a T helper 1 (Th-1) immune
response has been associated with increased responsiveness to immunotherapy and …
response has been associated with increased responsiveness to immunotherapy and …
Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis
J Roelands, M Van der Ploeg, ME Ijsselsteijn, H Dang… - Gut, 2023 - gut.bmj.com
Objective Biological insights into the stepwise development and progression of colorectal
cancer (CRC) are imperative to develop tailored approaches for early detection and optimal …
cancer (CRC) are imperative to develop tailored approaches for early detection and optimal …
[HTML][HTML] The immune landscape of solid pediatric tumors
Background Large immunogenomic analyses have demonstrated the prognostic role of the
functional orientation of the tumor microenvironment in adult solid tumors, this variable has …
functional orientation of the tumor microenvironment in adult solid tumors, this variable has …
Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data
According to publicly available transcriptome datasets, the abundance of Annexin A3
(ANXA3) is robustly increased during the course of sepsis; however, no studies have …
(ANXA3) is robustly increased during the course of sepsis; however, no studies have …
The MAPK hypothesis: immune-regulatory effects of MAPK-pathway genetic dysregulations and implications for breast cancer immunotherapy
With the advent of checkpoint inhibition, immunotherapy has revolutionized the clinical
management of several cancers, but has demonstrated limited efficacy in mammary …
management of several cancers, but has demonstrated limited efficacy in mammary …
BloodGen3Module: blood transcriptional module repertoire analysis and visualization using R
Motivation We previously described the construction and characterization of fixed reusable
blood transcriptional module repertoires. More recently we released a third iteration …
blood transcriptional module repertoires. More recently we released a third iteration …