The relevance of the nonclassical human leukocyte antigen (HLA) class I molecule HLA-G in
human physiological and pathological contexts has been the center of intense investigation …

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

Human leukocyte antigen G (HLA-G) is a nonclassic major histocompatibility complex
(MHC) class I molecule that functions as an immunomodulatory molecule capable of …

We recently reported that HLA-G1-transfected antigen-presenting cells (HLA-G1+ APCs)
were capable of inhibiting alloproliferative responses. The aim of the present work was to …

The nonclassical HLA class I antigen HLA‐G is an inhibitory molecule involved in immune
tolerance and immune escape. HLA‐G exerts its inhibitory functions via interaction with …

Major histocompatibility complex (mhc)–encoded molecules govern immune responses by
presenting antigenic peptides to T cells. The extensive polymorphism of genes encoding …

Trogocytosis is the uptake of membrane fragments from one cell by another and has been
described for immune cells in mice and humans. Functional consequences of trogocytosis …

Trogocytosis is a fast uptake of membranes and associated molecules from one cell by
another. Trogocytosis between natural killer (NK) cells and tumors is already described, but …

Context Overexpression of immune checkpoint molecules affects tumor-specific T-cell
immunity in the cancer microenvironment, and can reshape tumor progression and …

Peripheral T cell diversity is virtually constant in the young, but is invariably reduced in aged
mice and humans. CD8+ T cell clonal expansions (TCE) are the most drastic manifestation …